Dipeptidase E

Dipeptidase E
Pengidentifikasi
Nomor EC3.4.13.21
Basis data
IntEnztinjauan IntEnz
BRENDAentri BRENDA
ExPASytinjauan NiceZyme
KEGGentri KEGG
MetaCycjalur metabolik
PRIAMprofil
Struktur PDBRCSB PDB PDBe PDBsum
Dipeptidase E
Identifiers
OrganismeSalmonella typhimurium
SimbolPepE
UniProtP36936

Dipeptidase E (EC 3.4.13.21, aspartil dipeptidase, peptidase E, produk gen PepE (Salmonella typhimurium)) adalah sebuah enzim.[1][2] Enzim ini mengkatalisis reaksi kimia berikut:

Dipeptidase E mengkatalisis hidrolisis dipeptida Asp!Xaa. Enzim ini tidak bekerja pada peptida dengan N-terminal Glu, Asn, atau Gln, dan tidak memutus ikatan peptida isoaspartil.

Gugus karboksi bebas tidak mutlak diperlukan dalam substrat.

Referensi

  1. ^ Håkansson K, Wang AH, Miller CG (December 2000). "The structure of aspartyl dipeptidase reveals a unique fold with a Ser-His-Glu catalytic triad". Proceedings of the National Academy of Sciences of the United States of America. 97 (26): 14097–102. Bibcode:2000PNAS...9714097H. doi:10.1073/pnas.260376797. PMC 18877. PMID 11106384.
  2. ^ Lassy RA, Miller CG (May 2000). "Peptidase E, a peptidase specific for N-terminal aspartic dipeptides, is a serine hydrolase". Journal of Bacteriology. 182 (9): 2536–43. doi:10.1128/jb.182.9.2536-2543.2000. PMC 111318. PMID 10762256.

Pranala luar

Templat:Proteases Templat:Enzymes


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