Epoetin beta

Epoetin beta
Data klinis
Pengucapan/ɛˈpoʊ.ɪtɪn/
Nama dagangMircera, Recormon, dll[1]
AHFS/Drugs.comInternational Drug Names
License data
Kategori
kehamilan
Rute
pemberian		Intravena, subkutan
Kode ATC
Status hukum
Status hukum
  • AU: S4 (Prescription only) [2]
  • EU: Rx-only [3]
  • ℞ (Hanya resep)
Pengenal
Nomor CAS
DrugBank
ChemSpider
  • none
UNII
KEGG
 ☒NcheckY (what is this?)  (verify)

Epoetin beta (INN) adalah bentuk eritropoietin sintetis rekombinan,[4] suatu protein yang mendorong produksi sel darah merah. Obat ini adalah agen stimulan eritropoiesis (ESA) yang digunakan untuk mengobati anemia, yang umumnya terkait dengan gagal ginjal kronis dan kemoterapi kanker. Obat ini tercantum dalam Daftar Obat Esensial Organisasi Kesehatan Dunia.[5]

Sejarah

Epoetin beta adalah bentuk rekombinan eritropoietin manusia yang diproduksi di sel ovarium hamster Cina. Ia memiliki urutan protein yang sama dengan eritropoietin manusia alami, yang terdiri dari 165 asam amino dengan berat molekul sekitar 30 KDa.[6]

Referensi

  1. ^ Centers for Medicare and Medicaid Services: Erythrocyte Stimulating Agents Diarsipkan 2017-06-07 di Wayback Machine.. Retrieved 15 February 2017.
  2. ^ a b Australian product information Diarsipkan 2023-01-09 di Wayback Machine. guildlink.com.au
  3. ^ "NeoRecormon EPAR". European Medicines Agency (EMA). 17 September 2018. Diarsipkan dari versi aslinya tanggal 9 January 2023. Diakses tanggal 9 January 2023.
  4. ^ Dunn CJ, Markham A (February 1996). "Epoetin beta. A review of its pharmacological properties and clinical use in the management of anaemia associated with chronic renal failure". Drugs. 51 (2): 299–318. doi:10.2165/00003495-199651020-00008. PMID 8808169. S2CID 46985336.
  5. ^ World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.
  6. ^ Medsafe: Neorecormon Datasheet Diarsipkan 2020-08-30 di Wayback Machine.

Bacaan lebih lanjut

Pranala luar

  • "Epoetin beta". Drug Information Portal. U.S. National Library of Medicine. Diarsipkan dari asli tanggal April 7, 2020.

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