Ferokelatase
| Ferokelatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Ferokelatase manusia | |||||||||
| Pengidentifikasi | |||||||||
| Nomor EC | 4.99.1.1 | ||||||||
| Nomor CAS | 9012-93-5 | ||||||||
| Basis data | |||||||||
| IntEnz | tinjauan IntEnz | ||||||||
| BRENDA | entri BRENDA | ||||||||
| ExPASy | tinjauan NiceZyme | ||||||||
| KEGG | entri KEGG | ||||||||
| MetaCyc | jalur metabolik | ||||||||
| PRIAM | profil | ||||||||
| Struktur PDB | RCSB PDB PDBe PDBsum | ||||||||
| Ontologi Gen | AmiGO / EGO | ||||||||
| |||||||||
| Ferokelatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikasi | |||||||||
| Simbol | Ferokelatase | ||||||||
| Pfam | PF00762 | ||||||||
| InterPro | IPR001015 | ||||||||
| PROSITE | PDOC00462 | ||||||||
| SCOP | 1ak1 | ||||||||
| SUPERFAMILY | 1ak1 | ||||||||
| OPM superfamily | 129 | ||||||||
| OPM protein | 1hrk | ||||||||
| |||||||||
Ferokelatase adalah enzim yang berperan dalam tahap kedelapan atau terakhir dari sintesis heme pada sel makhluk hidup.[1] Pada tahap tersebut, enzim ini mengatalisis masuknya ion besi(II) (Fe2+) ke protoporfirin IX, menghasilkan heme B.[2] Reaksi yang dikatalisis ini dapat ditulis sebagai berikut:
- protoporfirin + Fe+2 ⇌ heme B + 2 H+
Referensi
- ^ Prof. Dr. Kris H. Timotius; Dr. Ivan Kurniadi, BMedSci(Hons). Heme: Biosintetis, Degradasi, serta Kelainan yang Dapat Menyertai. Penerbit Andi. hlm. 16. ISBN 978-979-29-6286-4. Diarsipkan dari asli tanggal 2023-07-20. Diakses tanggal 2018-12-30.
- ^ "Structure and function of ferrochelatase". Journal of Bioenergetics and Biomembranes. 25 (2): 221–9. 1995. Diarsipkan dari asli tanggal 2018-12-30. Diakses tanggal 2018-12-30. ;
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