Relaksin
| Relaxin 1 | |||||||
|---|---|---|---|---|---|---|---|
| Pengidentifikasi | |||||||
| Simbol | RLN1 | ||||||
| Simbol alternatif | H1 | ||||||
| Gen NCBI | 6013 | ||||||
| HGNC | 10026 | ||||||
| OMIM | 179730 | ||||||
| RefSeq | NM_006911 | ||||||
| UniProt | P04808 | ||||||
| Data lain | |||||||
| Lokus | Chr. 9 qter-q12 | ||||||
| |||||||
| Relaxin 2 | |||||||
|---|---|---|---|---|---|---|---|
| Pengidentifikasi | |||||||
| Simbol | RLN2 | ||||||
| Simbol alternatif | H2, RLXH2, bA12D24.1.1, bA12D24.1.2 | ||||||
| Gen NCBI | 6019 | ||||||
| HGNC | 10027 | ||||||
| OMIM | 179740 | ||||||
| PDB | 6RLX | ||||||
| RefSeq | NM_134441 | ||||||
| UniProt | P04090 | ||||||
| Data lain | |||||||
| Lokus | Chr. 9 qter-q12 | ||||||
| |||||||
| Relaxin 3 | |||||||
|---|---|---|---|---|---|---|---|
| Pengidentifikasi | |||||||
| Simbol | RLN3 | ||||||
| Simbol alternatif | ZINS4, RXN3, H3 | ||||||
| Gen NCBI | 117579 | ||||||
| HGNC | 17135 | ||||||
| OMIM | 606855 | ||||||
| RefSeq | NM_080864 | ||||||
| UniProt | Q8WXF3 | ||||||
| Data lain | |||||||
| Lokus | Chr. 19 p13.3 | ||||||
| |||||||
Relaksin adalah sebuah hormon protein hormone berkadar sekitar 6000 Da[1] yang pertama kali dideskripsikan pada tahun 1926 oleh Frederick Hisaw.[2][3] Keluarga peptida seperti relaksin masuk dalam keluarga besar insulin dan terdiri dari 7 peptidal berstruktur tinggi tetapi kesamaan urutannya rendah; relaxin-1 (RLN1), 2 (RLN2) and 3 (RLN3), dan peptida-peptida mirip insulin (INSL), INSL3, INSL4, INSL5 dan INSL6. Fungsi relaxin-3, INSL4, INSL5, dan INSL6 masih belum dikarakterisasikan.[4]
Referensi
- ^ Bani D (Januari 1997). "Relaxin: a pleiotropic hormone". General Pharmacology. 28 (1): 13–22. doi:10.1016/s0306-3623(96)00171-1. PMID 9112071.
{{cite journal}}: Pemeliharaan CS1: Tanggal diterjemahkan otomatis (link) - ^ "If a Gopher Can Do It …". Time Magazine. 1944-04-10. Diarsipkan dari asli tanggal Desember 15, 2008. Diakses tanggal 2009-05-20.
{{cite web}}: Pemeliharaan CS1: Tanggal diterjemahkan otomatis (link) - ^ Becker GJ, Hewitson TD (Maret 2001). "Relaxin and renal fibrosis". Kidney International. 59 (3): 1184–5. doi:10.1046/j.1523-1755.2001.0590031184.x. PMID 11231378.
{{cite journal}}: Pemeliharaan CS1: Tanggal diterjemahkan otomatis (link) - ^ Wilkinson TN, Speed TP, Tregear GW, Bathgate RA (Februari 2005). "Evolution of the relaxin-like peptide family". BMC Evolutionary Biology. 5: 14. doi:10.1186/1471-2148-5-14. PMC 551602. PMID 15707501.
{{cite journal}}: Pemeliharaan CS1: DOI bebas tanpa ditandai (link) Pemeliharaan CS1: Tanggal diterjemahkan otomatis (link)
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