Ribozim

Struktur ribozim martil.

Ribozim (ribonucleic acid enzyme, bahasa Indonesia: enzim asam ribonukleat) adalah molekul RNA yang mengatalisis reaksi kimia. Enzim asam ribonukleat juga dapat disebut enzim RNA atau RNA katalitis. Ribozim alami mengatalisis hidrolisis ikatan fosfodiester mereka sendiri, atau hidrolisis ikatan di RNA lain. Beberapa ribozim mengatalisis aktivitas aminotransferase pada ribosom. Contoh ribozim adalah ribozim martil, ribozim VS, dan ribozim jepit rambut.[1][2][3]

Rujukan

  1. ^ Doherty EA, Doudna JA (2001). "Ribozyme structures and mechanisms". Annu Rev Biophys Biomol Struct. 30: 457–75. doi:10.1146/annurev.biophys.30.1.457. PMID 11441810.
  2. ^ Joyce GF (2004). "Directed evolution of nucleic acid enzymes". Annu. Rev. Biochem. 73: 791–836. doi:10.1146/annurev.biochem.73.011303.073717. PMID 15189159.
  3. ^ Ikawa Y, Tsuda K, Matsumura S, Inoue T (2004). "De novo synthesis and development of an RNA enzyme". Proc. Natl. Acad. Sci. U.S.A. 101 (38): 13750–5. doi:10.1073/pnas.0405886101. PMC 518828. PMID 15365187. Pemeliharaan CS1: Banyak nama: authors list (link)


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