Autofagi

Ikke at forveskle med autofagia (selvskade ved spisning af egne legemsdele)

Autofagi (fra oldgræsk αὐτόφαγος autóphagos, der betyder "selvspisende") (også kaldet autofagocytose) er den naturlige og regulerede nedbrydning af cellens bestanddele, der foregår i cellens lysosomer.[1] Autofagi gør det muligt på en kontrolleret måde at nedbryde og genbruge de dele af cellen, der måtte være uønskede eller er defekte.[2][3]

Referencer

  1. ^ Klionsky, D.J. (2008) Autophagy revisited: a conversation with Christian de Duve. Autophagy 4: 740-3. doi: 10.4161/auto.6398. PMID 18567941.
  2. ^ Mizushima, N., Komatsu, M. (2011) Autophagy: renovation of cells and tissues. Cell 147: 728-41. doi: 10.1016/j.cell.2011.10.026. PMID 22078875.
  3. ^ Kobayashi, S. (2015) Choose Delicately and Reuse Adequately: The Newly Revealed Process of Autophagy. Biological and Pharmaceutical Bulletin 38: 1098-103. doi: 10.1248/bpb.b15-00096. PMID 26235572.
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