Filcon

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Filconer er polymerer, der specielt bruges i kontaktlinser. Ordet er en sammentrækning af "hydrofil" og "contact lens", og står i modsætning til focon som betegner hydrofobe kontaktlinsepolymere.[1][2] Ordet bruges oftes som suffix i navne på specifikke kontaktlinsepolymere fx "Nelfilcon", "Etafilcon", "Methafilcon".

Filconer danner bløde hydrogeler dvs. blød plast med et naturligt højt indhold af vand, hvilket er den ønskværdige materialeegenskab for bløde kontaktlinser.

Monomererne anvendt i filconer

Polymerer består af gentagende enkelt dele kaldet monomere. Gennembruddet for filconer kom med polymeriseringen af 2-hydroxyethyl methacrylat i 1960. Efterfølgende er co-polymerisering med andre monomere resulteret i det store udvalg af filconer, der eksisterer i dag.

CH2=C(CH3)COO-CH2CH2OH

Monomerenen 2-hydroxyethyl methacrylat.

(-CH2-C[(CH3)COO-CH2CH2OH]-)n

Polymeren dannet ud fra 2-hydroxyethyl methacrylat.

Filiconer og monomerer

For udvalgte filconer, er deres monomere givet i tabellen nedenfor og som det fremgår, består filconer normalt af flere co-polymeriserede typer af monomere.

Filcon Monomere Kemisk formel
Polymacon 2-hydroxyethyl methacrylat
ethylenglycol dimethacrylat		 CH2=C(CH3)COO-CH2CH2OH
CH2=C(CH3)COO-CH2CH2-OOCC(CH3)=CH2
Etafilcon A 2-hydroxyethyl methacrylat
natrium methacrylat
2-ethyl-2-(hydroxymethyl)-1,3-propandiol trimethacrylat		 CH2=C(CH3)COO-CH2CH2OH
CH2=C(CH3)COONa
[CH2=C(CH3)COO-]3CCH2CH3
Ocufilcon A / C 2-hydroxyethyl methacrylat
methacrylsyre
ethylenglycol dimethacrylat		 CH2=C(CH3)COO-CH2CH2OH
CH2=C(CH3)COOH
CH2=C(CH3)COO-CH2CH2-OOCC(CH3)=CH2

Reference [3]

Kontaklinseprodukter og filconer

En liste over kontaktlinseprodukter og tilhørende polymere findes i tabellen nedenfor.

Produkt Polymer
Cibasoft, Illusions, Torisoft Tefilcon
CooperToric, Preference, Preference Toric, Vantage Tetrafilcon A
CSI, CSI Toric Crofilcon
Focus Night & Day Lotrafilcon A
O2Optix Lotrafilcon B
Acuvue Advance with Hydraclear, Advance for Astigmatism Galyfilcon A
Acuvue Oasys Senofilcon A
Soflens 66 Alfafilcon A
Proclear Compatibles Omafilcon A
Focus Dailies, Dailies Toric Nelfilcon A
Soflens 1-day Hilafilcon A
Soflens 59 Hilafilcon B
Durasoft 2 Phemfilcon A
Purevision Balafilcon A
Acuvue, Acuvue Bifocal, Acuvue 2, Acuvue 1-day Etafilcon A
Biomedics 55, Biomedics 55 Premier Ocufilcon D
Durasoft 3, Freshlook, Wildeyes Phemfilcon A
Sunsoft Eclipse, Revolution, Sunsoft Toric Methafilcon A
Focus 1-2 Week, Focus Toric, Focus Progressives Vilfilcon A

Reference [4]

Referencer

  1. ^ Ordet "filcon" Arkiveret 7. april 2014 hos Wayback Machine, .
  2. ^ Ordet "filcon" Arkiveret 7. april 2014 hos Wayback Machine, .
  3. ^ Biomaterials Science: An Introduction to Materials in Medicine af Buddy D. Ratner, Allan S. Hoffman, Frederick J. Schoen og Jack E. Lemons, Academic Press.
  4. ^ Kontaktlinseprodukt og tilsvarende filcon Arkiveret 7. april 2014 hos Wayback Machine, .

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