Mosaicisme
Mosaicisme er en tilstand, hvor to eller flere cellepopulationer med forskellige genotyper forekommer i ét individ, der er udviklet fra én zygote.[1] Disse personer siges at være mosaikker og er ikke at forveksle med kimære, hvor der i ét individ forekommer cellepopulationer, der er udviklet fra forskellige zygoter. Der findes to slags mosaicisme:
- Somatisk mosaicisme i den somatiske cellelinje
- Kønscellemosaicisme i kønscellelinjen
Mosaicisme skyldes ofte non-disjunction i mitosen.
Referencer
- ^ Marchi, M. De; et al. (2008). "True hermaphroditism with XX/XY sex chromosome mosaicism: Report of a case". Clinical Genetics. 10 (5): 265-72. doi:10.1111/j.1399-0004.1976.tb00047.x. PMID 991437.
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