On October 7, 1939, the Aggies opened their season with a 26 to 13 victory over Michigan. The game, the 34th played between the two programs,[9] was played at Michigan Stadium before 68,618 spectators that The New York Times called "a howling throng."[10]
Michigan took a 26 to 0 lead at halftime. The Wolverines' first points came on three-yard run around the right end by Paul Kromer, with blocking by Tom Harmon and Forest Evashevski, capping a 65-yard touchdown drive. On the opening play of the second quarter, Harmon scored on a two-yard run, capping a drive that started at Michigan State's 33-yard line. On the ensuing Michigan State drive, Archie Kodros intercepted a pass at the Spartans' 20-yard line, and after a 15-yard penalty was assessed, Michigan took over on the five-yard line. From there, Harmon threw a touchdown pass to Evashevski. Michigan's final score followed a second interception by Kodros, with Kodros catching the ball at the 45-yard line and returning it 17 yards to the 28-yard line. On fourth down from the four-yard line, Harmon threw his second touchdown pass to Evashevski. In the third quarter, Bill Batchelor of Michigan State intercepted a pass and returned it 25 yards for a touchdown. In the fourth quarter, the Spartans scored again on a 71-yard pass play from Bill Kennedy to Wyman Davis. Harmon and William Melzow each kicked one point after touchdown (PAT) in the game.[10][11]