The 2006 Kilkenny Senior Hurling Championship was the 112th staging of the Kilkenny Senior Hurling Championship since its establishment by the Kilkenny County Board. The championship began on 24 September 2006 and ended on 5 November 2006.
On 5 November 2006, Ballyhale Shamrcks won the title after a 1–22 to 2–11 defeat of O'Loughlin Gaels in the final at Nowlan Park.[2] It was their 10th championship title overall and their first title since 1991.