The 2021 Prague Open (branded as the 2021 Livesport Prague Open for sponsorship reasons) was a professional women's tennis tournament played on outdoor hard courts at the TK Sparta Prague. It was the 12th (WTA and non-WTA) edition of the tournament which was part of the 2021 WTA Tour, and of the 250 series of tournaments. It took place in Prague, Czech Republic between 12 and 18 July 2021. This was the first edition of the tournament held on outdoor hard courts, as opposed to clay courts in previous editions.[1]
Bold denotes the mandatory tournaments (WTA 1000) † – Tournaments are affected by the COVID-19 pandemic * – Tournaments are introduced due to the impact of the COVID-19 pandemic