The 2022 Kobe Challenger was a professional tennis tournament played on indoor hard courts. It was the 6th edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Kobe, Japan between 14 and 20 November 2022.
The following players received wildcards into the singles main draw:
The following players received entry into the singles main draw using protected rankings:
The following players received entry from the qualifying draw:
