2022 Mutua Madrid Open – Men's doubles

Wesley Koolhof and Neal Skupski defeated Juan Sebastián Cabal and Robert Farah in the final, 6–7^(4–7), 6–4, [10–5] to win the men's doubles tennis title at the 2022 Madrid Open. It was their first ATP Masters 1000 title.

Marcel Granollers and Horacio Zeballos were the defending champions,^[1] but lost in the quarterfinals to Cabal and Farah.

This tournament marked the final professional appearance of former doubles world No. 3 and Olympic gold medalist Marc López.^[2]

	Semifinals							Final
		Hubert Hurkacz John Isner	67	5
	7	Wesley Koolhof Neal Skupski	79	7
								7	Wesley Koolhof Neal Skupski	64	6	[10]
								5	Juan Sebastián Cabal Robert Farah	77	4	[5]
	8	Jamie Murray Michael Venus	63	3
	5	Juan Sebastián Cabal Robert Farah	77	6

	First round							Second round							Quarterfinals							Semifinals
								1	R Ram J Salisbury	4	4
		M Arévalo J-J Rojer						PR	K Krawietz A Mies	6	6
	PR	K Krawietz A Mies	w/o												PR	K Krawietz A Mies	6	65	[5]
		H Hurkacz J Isner	6	3	[10]											H Hurkacz J Isner	4	77	[10]
		A Behar G Escobar	3	6	[7]				H Hurkacz J Isner	6	6
		K Khachanov A Rublev	7	6					K Khachanov A Rublev	3	4
	6	J Peers F Polášek	5	4																			H Hurkacz J Isner	67	5
																						7	W Koolhof N Skupski	79	7
								4	P-H Herbert N Mahut	6	63	[6]
		T Brkić N Ćaćić	78	710					T Brkić N Ćaćić	4	77	[10]
	Alt	F Delbonis A Molteni	66	68												T Brkić N Ćaćić	3	78	[2]
	PR	Ł Kubot É Roger-Vasselin	6	62	[4]										7	W Koolhof N Skupski	6	66	[10]
	WC	C Alcaraz M López	4	77	[10]			WC	C Alcaraz M López	3	6	[7]
	Alt	N Basilashvili A Bublik	5	2				7	W Koolhof N Skupski	6	3	[10]
	7	W Koolhof N Skupski	7	6

	First round							Second round							Quarterfinals							Semifinals
	8	J Murray M Venus	6	3	[10]
	WC	P Tsitsipas S Tsitsipas	2	6	[7]			8	J Murray M Venus	6	6
		C Norrie T Paul	3	6	[10]				C Norrie T Paul	4	3
		M Melo A Zverev	6	3	[7]										8	J Murray M Venus	77	79
		A Golubev S González	6	1	[8]											S Bolelli I Dodig	65	67
		S Bolelli I Dodig	3	6	[10]				S Bolelli I Dodig	7	3	[10]
								3	N Mektić M Pavić	5	6	[6]
																						8	J Murray M Venus	63	3
	5	JS Cabal R Farah	68	77	[11]																	5	JS Cabal R Farah	77	6
		R Klaasen B McLachlan	710	63	[9]			5	JS Cabal R Farah	w/o
		M González D Schwartzman	3	68					F Auger-Aliassime G Dimitrov
		F Auger-Aliassime G Dimitrov	6	710											5	JS Cabal R Farah	77	6
	WC	P Carreño Busta P Martínez	66	6	[10]										2	M Granollers H Zeballos	65	4
		R Bopanna D Shapovalov	78	3	[1]			WC	P Carreño Busta P Martínez	68	6	[5]
								2	M Granollers H Zeballos	710	2	[10]

The following are the seeded teams, based on ATP rankings as of April 25, 2022.

Country	Player	Country	Player	Rank	Seed
USA	Rajeev Ram	GBR	Joe Salisbury	3	1
ESP	Marcel Granollers	ARG	Horacio Zeballos	9	2
CRO	Nikola Mektić	CRO	Mate Pavić	9	3
FRA	Pierre-Hugues Herbert	FRA	Nicolas Mahut	15	4
COL	Juan Sebastián Cabal	COL	Robert Farah	26	5
AUS	John Peers	SVK	Filip Polášek	26	6
NED	Wesley Koolhof	GBR	Neal Skupski	32	7
GBR	Jamie Murray	NZL	Michael Venus	33	8

Before the tournament

• Marcelo Arévalo / Jean-Julien Rojer
• Taylor Fritz / Reilly Opelka → replaced by Federico Delbonis / Andrés Molteni
• Sander Gillé / Joran Vliegen → replaced by Nikoloz Basilashvili / Alexander Bublik
• Tim Pütz / Michael Venus → replaced by Jamie Murray / Michael Venus

• Main draw