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AHCTF1
Identifiers
Aliases	AHCTF1, ELYS, MST108, TMBS62, MSTP108, AT-hook containing transcription factor 1
External IDs	OMIM: 610853; MGI: 1915033; GeneCards: AHCTF1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4I0O
Gene location (Human)
Chr.	Chromosome 1 (human)
End	246,931,948 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	179,631,245 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; Achilles tendon; ; secondary oocyte; ; sperm; ; ventricular zone; ; Brodmann area 23; ; testicle; ; internal globus pallidus; ; left testis; ; middle temporal gyrus;
	Top expressed in
	tail of embryo; ; spermatocyte; ; spermatid; ; genital tubercle; ; epiblast; ; seminiferous tubule; ; zygote; ; secondary oocyte; ; otic placode; ; otic vesicle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; cytosol; nuclear membrane; nuclear periphery; nuclear matrix; nuclear pore; nucleoplasm; chromosome; nuclear pore outer ring; chromatin; extracellular exosome; chromosome, centromeric region; nucleus; kinetochore; nuclear envelope;
Biological process	mRNA transport; nuclear pore complex assembly; regulation of transcription, DNA-templated; cytokinesis; cell division; protein transport; cell cycle; sister chromatid cohesion; transport; regulation of transcription by RNA polymerase II; regulation of cytokinesis;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	25909
	226747
	ENSG00000153207
	ENSMUSG00000026491
	Q8WYP5
	Q8CJF7
	NM_015446; NM_001323342; NM_001323343; NM_175865
	NM_026375
	NP_001310271; NP_001310272; NP_056261
	NP_080651
	Wikidata
View/Edit Human	View/Edit Mouse

Protein ELYS is a protein that in humans is encoded by the AHCTF1 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000153207 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026491 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kimura N, Takizawa M, Okita K, Natori O, Igarashi K, Ueno M, Nakashima K, Natori O, Nobuhisa I, Taga T (Apr 2002). "Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues". Genes Cells. 7 (4): 435–46. doi:10.1046/j.1365-2443.2002.00529.x. PMID 11952839. S2CID 22977237.
^ "Entrez Gene: AHCTF1 AT hook containing transcription factor 1".

External links

Human AHCTF1 genome location and AHCTF1 gene details page in the UCSC Genome Browser.

Rasala BA, Orjalo AV, Shen Z, et al. (2007). "ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division". Proc. Natl. Acad. Sci. U.S.A. 103 (47): 17801–6. doi:10.1073/pnas.0608484103. PMC 1635652. PMID 17098863.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000153207 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026491 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11952839-5] Kimura N, Takizawa M, Okita K, Natori O, Igarashi K, Ueno M, Nakashima K, Natori O, Nobuhisa I, Taga T (Apr 2002). "Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues". Genes Cells. 7 (4): 435–46. doi:10.1046/j.1365-2443.2002.00529.x. PMID 11952839. S2CID 22977237.

[entrez-6] "Entrez Gene: AHCTF1 AT hook containing transcription factor 1".

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AHCTF1

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