Abraxis BioScience
Abraxis BioScience was a global biopharmaceutical, and nano-medicine company that developed treatments for critically ill patients. It had over 2000 employees worldwide in 2007.[3] Abraxis's portfolio included the world's first protein-based nanoparticle chemotherapeutic compound, called nab Technology.[4] From this the company developed Abraxane, a treatment for metastatic breast cancer.[5] In 2010, Abraxis BioScience was acquired by Celgene Corporation.[6] HistoryAbraxis was incorporated in 2001 in Los Angeles.[1] It was formerly known as American Pharmaceutical Partners (APP), which as known for its injectable oncology, anti-infective and critical care.[7] Besides cancer treatments, it provided treatment for multiple sclerosis, Alzheimer's, and some cardiovascular diseases.[1] It had manufacturing plants in Melrose Park, Illinois and Phoenix, Arizona.[1] By 2005, Dr. Patrick Soon-Shiong merged American BioScience and the publicly-held APP, naming it Abraxis BioScience.[8] Under this new name, seventy-four trials were undertaken to test Abraxane against various cancer targets.[8] The drug, which was approved by the FDA in 2005, was the subject of a litigation (Elan Pharma v. Abraxis BioScience) for patent infringement.[9] In 2008, Abraxis was ordered to pay $55.2 million to Elan.[9] In August 2007, Abraxis announced it would again undergo a restructuring to separate its "hospital-based products business" from its "proprietary products business" into two public companies; this would involve the merging of Abraxis Oncology and Abraxis Research sub-units to form a new Abraxis Bioscience (Abraxis Bioscience, Inc., Nasdaq: ABII), and the spinoff of Abraxis Pharmaceutical Products (APP, Inc., Nasdaq: APPX).[10] This reorganization was completed in November 2007.[11] During the reorganization, the new Abraxis Bioscience was known briefly as New Abraxis.[11] In 2010, Abraxis BioScience was acquired by Celgene Corporation.[6] Per Celgene's website, as of at least 2016 Abraxis no longer exists as a named division within Celgene.[citation needed] References
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