A keen rock climber and ballerina as a child, Azkona started her career playing futsal for Gazte Berriak, a team based in Ansoain.[3] Following this, she spent a year at Ardoi before signing for Athletic Club aged 18.[4] On 13 January 2019, she scored her first league goal for Athletic, in the 94th minute of a match against Sporting de Huelva.[5][6] In the 2019–20 Primera División season, she provided more assists than any other Athletic player and signed a new three-year contract with the club at the end of that season.[7][8]
On 10 June 2020, it was announced that she had torn the anterior cruciate ligament in her right knee during a training session.[9] She returned from this injury over eight months later.[7] She became an increasingly important member of the team over the subsequent seasons as other players departed;[3] in March 2023 she agreed a new contract running to 2026.[10]
^Carlos Zaballa (24 March 2023). ""Yo también me he subido a este barco"" ["I have also boarded this boat"]. Mundo Deportivo (in Spanish). Retrieved 12 December 2023.