ARTIKELDIGITAL.COM

Victims (BRCT; Bengali: বিআরসিটি) is a Bangladeshi NGO, working in the area of rehabilitation of trauma victims. It was established in 1992. BRCT began its...

BRCA1 C Terminus (BRCT) domain is a family of evolutionarily related proteins. It is named after the C-terminal domain of BRCA1, a DNA-repair protein that...

repeat BRCT domain of the BRCA1 protein is an elongated structure approximately 70 Å long and 30–35 Å wide. The 85–95 amino acid domains in BRCT can be...

a tumor suppressor, by binding to the C terminus between repeats in the BRCT domain. Like the ATPase activity, this interaction depends on phosphorylation...

partners through its breast cancer associated gene 1 C-terminus (BRCT) domains. A BRCT domain is structurally defined by a 4 member β sheet that is bookended...

Pavletich NP (Mar 2002). "Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure". Genes & Development. 16 (5): 583–93...

famous example is the case of tandem BRCT domains, found in the tumor suppressor protein BRCA1. While individual BRCT domains are found in certain proteins...

(residues 46-90), four ankyrin repeats (residues 420-555), and a tandem BRCT domain (residues 568-777). Most, if not all, BRCA1 heterodimerizes with BARD1...

suppressor protein p53. This protein also goes by the name Nuclear Factor with BRCT Domain 1 (NFBD1). The MDC1 gene encodes the MDC1 nuclear protein which is...

the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role...

Pavletich NP (March 2002). "Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure". Genes & Development. 16 (5): 583–93...

TOPBP1. The Rad9 protein contains a carboxy-terminal tandem repeat of the BRCT (BRCA1 carboxyl terminus) motif, which is found in many proteins involved...

the paired box (PAX) gene family and encodes a nuclear protein with six BRCT (breast cancer carboxy-terminal) domains. This protein plays a critical role...

Longhorn Council Palo Pinto, TX Active Includes the Brazos River Canoe Trip (BRCT) high adventure trip. In operation since 1929. Cub Resident Camp debuted...

structurally and functionally related to pol λ, and, like pol λ, pol μ has a BRCT domain that is thought to mediate interactions with other DNA repair proteins...

primers with terminal mismatches. Rev1 has three regions of interest in the BRCT domain, ubiquitin-binding domain, and C-terminal domain and has dCMP transferase...

The XRCC1 N-terminal domain binds to DNA polymerase beta, the C-terminal BRCT domain interacts with DNA ligase III alpha and the central domain contains...

Flom, LLP) (September 23, 2009), RE: WWOR-TV Renewal Application File No. BRCT-20070201AJT Notice of Ex Parte Presentation MB Docket No. 07-260, archived...

and a BRCT domain. The 8 kDa domain has lyase activity that can remove a 5' deoxyribosephosphate group from the end of a strand break. The BRCT domain...

Z (2004). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". J. Biol. Chem. 278 (52): 52914–8. doi:10.1074/jbc.C300407200....

functions as a post-translational modification, and binding domains such as BRCT have been characterised. Histone modifications are involved in control of...

http://thebiogrid.org/149877/publication/charting-the-landscape-of-tandem-brct-domain-mediated-protein- interactions.html "PSICQUIC View". "STRING: Functional...

Flom, LLP (September 23, 2009), RE: WWOR-TV Renewal Application File No. BRCT-20070201AJT Notice of Ex Parte Presentation MB Docket No. 07-260, archived...

PMID 29685496. Lechner MS, Levitan I, Dressler GR (Jul 2000). "PTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associated with active...

Tomlinson G, Osborne CK, Sharp ZD, Lee WH (April 1999). "Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted...

physiological stress over time. LIG4 has been shown to interact with XRCC4 via its BRCT domain. This interaction stabilizes LIG4 protein in cells; cells that are...

following three domains: N-terminal BRCT domain Central microcephalin protein domain (InterPro: IPR022047) C-terminal BRCT domain MCPH1 is expressed in the...

Tong L (May 2008). "Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1". Biochemistry...

Z (2004). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". J. Biol. Chem. 278 (52): 52914–8. doi:10.1074/jbc.C300407200....

PMC 444862. PMID 15254234. Kim JE, Billadeau DD, Chen J (2005). "The tandem BRCT domains of Ect2 are required for both negative and positive regulation of...

recognizes distinctly different protein motifs from CtBP. CtIP binds to the BRCT repeats within the breast cancer gene BRCA1 and enables CtBP to influence...

Huang D, Pospiech H, Majuri I, Westerling T, Mäkelä TP, Syväoja JE (2001). "BRCT domain-containing protein TopBP1 functions in DNA replication and damage...

Z (2004). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". J. Biol. Chem. 278 (52): 52914–8. doi:10.1074/jbc.C300407200....

tumors of astrocytic origin. It is a strongly conserved gene containing a BRCT domain that is essential for the activity of this gene product. The gene...

Z (2003). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". J. Biol. Chem. 278 (52): 52914–8. doi:10.1074/jbc.C300407200....

encoding a C-terminal breast cancer susceptibility protein 1 C-terminal (BRCT) domain at the C-terminus of DNA ligase III-alpha is replaced by a short...

histone H2AX and NBS1. NBS1 relocates to DSB sites by interaction of FHA/BRCT domains with phosphorylated histone H2AX. Once it interacts with nibrin c-terminal...

This phosphorylation generates binding sites for adaptor proteins with a BRCT domain. These adaptor proteins then recruit different factors including the...

Biddeford , York County , Maine 04005 Information School type Vocational School Director Paulette Bonneau Website https://www.biddefordschools.me/o/brct...

PMID 14517542. S2CID 22461437. Yu X, Chini CC, He M, et al. (2003). "The BRCT domain is a phospho-protein binding domain". Science. 302 (5645): 639–42...

Z (2004). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". J. Biol. Chem. 278 (52): 52914–8. doi:10.1074/jbc.C300407200....

pairs of BRCA1 C Terminus (BRCT) domains which are known as a phosphopeptide-binding domains. The N-terminal pair of the BRCT domains binds to phosphorylated...

complexed with a quinoxaline-type inhibitor 2cok: Solution structure of BRCT domain of poly(ADP-ribose) polymerase-1 2cr9: Solution structure of WGR domain...

problems ranging from DNA repair proteins like AP endonuclease to XRCC1 BRCT in collaboration with Tomas Lindahl's group, PML (promyelocytic leukemia...

PMID 8405995. Liu K, Lin FT, Ruppert JM, Lin WC (May 2003). "Regulation of E2F1 by BRCT domain-containing protein TopBP1". Mol. Cell. Biol. 23 (9): 3287–304. doi:10...

can be disrupted by interaction of the C-terminal domain of XRCC4 with the BRCT domain of DNA ligase IV. Deficiency of NHEJ1 in mice leads to premature aging...

(December 2003). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". The Journal of Biological Chemistry. 278 (52): 52914–52918. doi:10...

PMID 9244435. Yu X, Wu LC, Bowcock AM, Aronheim A, Baer R (1998). "The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the...

(October 2002). "NBS1 localizes to γH2AX foci through interaction with the FHA/BRCT domain". Current Biology. 12 (21): 1846–1851. Bibcode:2002CBio...12.1846K...

(December 2003). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". The Journal of Biological Chemistry. 278 (52): 52914–52918. doi:10...

State Technological Invention Award (Third Class) for the titanium alloy BRCT heat treatment process 1997 Member of the Chinese Academy of Sciences (CAS)...

(December 2003). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains". The Journal of Biological Chemistry. 278 (52): 52914–52918. doi:10...

the two alpha helical tails. The helix-loop-helix clamp connected to the BRCT-linker also makes extensive contacts. The process of NHEJ involves XRCC4...