Goldacre is known in particular for his Bad Science column in The Guardian, which he wrote between 2003 and 2011, and is the author of four books: Bad Science (2008), a critique of irrationality and certain forms of alternative medicine; Bad Pharma (2012), an examination of the pharmaceutical industry, its publishing and marketing practices, and its relationship with the medical profession;[12]I Think You'll Find It's a Bit More Complicated Than That,[13] a collection of his journalism; and Statins, about evidence-based medicine.[14] Goldacre frequently delivers free talks about bad science; he describes himself as a "nerd evangelist".[15][16][17]
In 2015, Goldacre moved to the Nuffield Department of Primary Care Health Sciences's Centre for Evidence-Based Medicine at the University of Oxford, joining a project funded by a grant from the Laura and John Arnold Foundation.[35] In 2022, he became the first Bennett Professor of Evidence-Based Medicine and director of Oxford's newly-established Bennett Institute for Applied Data Science.[7]
In 2020, Goldacre was, with Liam Smeeth, the principal investigator of the OpenSAFELY collaboration which created a software platform to analyse the records of 24 million NHS patients to provide detailed risk factors for hospital deaths from COVID-19.[43][44]
"Bad Science" Guardian column and blog
Goldacre was known for his weekly column, "Bad Science", which ran in the Saturday edition of The Guardian from 2003[45] until November 2011.[46] The column largely concerned pseudoscience and the misuse of science. Topics discussed included marketing, the media, quackery, problems with the pharmaceutical industry, and its relationship with medical journals.[47][48][49]
He has been a particularly harsh critic of the nutritionist Gillian McKeith.[56] While investigating McKeith's membership of the American Association of Nutritional Consultants, Goldacre obtained a professional membership on behalf of his late cat, Henrietta, from the same institution for $60.[57] In February 2007, McKeith agreed to stop using the title "Doctor" in her advertising, following a complaint to the Advertising Standards Authority by a "Bad Science" reader.[58] In an interview with Richard Saunders of the podcast Skeptic Zone, Goldacre said, "Nutritionists are particularly toxic because they are the alternative therapists who, more than any other, misrepresent themselves as being men and women of science."[59]
In 2008, Matthias Rath, a vitamin entrepreneur, sued Goldacre and The Guardian over three articles,[60][61][62] in which Goldacre criticised Rath's promotion of vitamin pills to AIDS sufferers in South African townships.[63] Rath dropped his action in September 2008 and was ordered to pay initial costs of £220,000 to The Guardian.[63] As of September 2008, the paper was seeking full costs of £500,000, and Goldacre had expressed an interest in writing a book about Rath and South Africa, as a chapter on the subject had to be cut from his book while the litigation proceeded.[64] The chapter was reinstated in a later edition of the book, and also published online in 2009.[65] Goldacre continues to cite Rath as a proponent of harmful pseudoscience.[66]
Although challenging Andrew Wakefield's views about immunisation, Goldacre repeatedly defended Wakefield against an investigation by The Sunday Times into Wakefield's fraudulent 1998 paper in The Lancet, prompting criticism from the newspaper's reporter Brian Deer.[67]
Writing in The Guardian in September 2005, Goldacre argued:
The paper always was and still remains a perfectly good small case series report, but it was systematically misrepresented as being more than that, by media that are incapable of interpreting and reporting scientific data.[68]
After Wakefield's falsifications of the data came to light, Goldacre continued to lambast journalists for credulity and sensationalism:
Even if it had been immaculately well conducted - and it certainly wasn’t – Wakefield’s "case series report" of 12 children’s clinical anecdotes would never have justified the conclusion that MMR causes autism, despite what journalists claimed: it simply didn’t have big enough numbers to do so.[69]
Goldacre's first book, Bad Science, was published by Fourth Estate in September 2008.[70] The book contains extended and revised versions of many of his Guardian columns. It was positively reviewed by the British Medical Journal (BMJ) and The Daily Telegraph, and reached the Top 10 bestseller list for Amazon Books.[71] It was nominated for the 2009 Samuel Johnson Prize.[72][73] In an interview in 2008, Goldacre said that "one of the central themes" of his book [Bad Science] was "that there are no real differences between the $600 billion pharmaceutical industry and the $50 billion food supplement pill industry."[74]
His second book, Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients, was published in the UK in September 2012 and in the United States and Canada in February 2013.[75] In the book he argues that:
Drugs are tested by the people who manufacture them, in poorly designed trials, on hopelessly small numbers of weird, unrepresentative patients, and analysed using techniques which are flawed by design, in such a way that they exaggerate the benefits of treatments. Unsurprisingly, these trials tend to produce results that favour the manufacturer. When trials throw up results that companies don't like, they are perfectly entitled to hide them from doctors and patients, so we only ever see a distorted picture of any drug's true effects. Regulators see most of the trial data, but only from early on in a drug's life, and even then they don't give this data to doctors or patients, or even to other parts of government. This distorted evidence is then communicated and applied in a distorted fashion. In their forty years of practice after leaving medical school, doctors hear about what works through ad hoc oral traditions, from sales reps, colleagues or journals. But those colleagues can be in the pay of drug companies – often undisclosed – and the journals are too. And so are the patient groups. And finally, academic papers, which everyone thinks of as objective, are often covertly planned and written by people who work directly for the companies, without disclosure.[76]
Other journalism, writing and appearances
Goldacre contributed to The Atheist's Guide to Christmas (2009), a charity book featuring essays and anecdotes from 42 well-known atheists and apatheists, on the subject of "the power of ideas".[77] He describes himself as an apatheist.[78] He also wrote the foreword to a reissue of Testing Treatments: Better Research for Better Healthcare by Imogen Evans, Hazel Thornton, Iain Chalmers and Paul Glasziou, published by Pinter & Martin in March 2010. He has had several articles published in the British Medical Journal (BMJ) on the MMR vaccine,[79] science journalism,[80][81] and related topics.[82][83]
Association of British Science Writers award for Best Feature 2005 for his article "Don't dumb me down".[92]
Freelance of 2006 at the Medical Journalism Awards.[93]
The Committee for Skeptical Inquiry (CSICOP) presented in 2006 the Balles Prize in Critical Thinking award for his column in The Guardian U.K. newspaper, Bad Science Columns include "Dyslexia 'cure' fails to pass the tests", "Bring me a God helmet, and bring it now", "Kick the habit with wacky wave energy", "Brain Gym exercises do pupils no favors" and "Magnetic attraction? Shhhh. It's a secret"[94]
The inaugural Statistical Excellence In Journalism Award of the Royal Statistical Society[1] for his article "When the facts get in the way of a story".[95]
The Philosophy Now Award for Contributions in the Fight Against Stupidity (2012).[96]
^Kmietowicz, Z. (2012). "Health minister agrees to meet academics to discuss access to clinical trial data". BMJ. 345 (oct23 4): e7168. doi:10.1136/bmj.e7168. PMID23093027. S2CID32288096.
^Saunders, Richard. "The Skeptic Zone #16 – 06.Feb.2009". The Skeptic Zone. Retrieved 14 May 2014. There are bad things happening in medicine and academia but people talk about them, people criticize them, you know, and in the world of alternative therapies, you can be as far out as Matthias Rath and nobody will say a word.
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