CRELD1

CRELD1
Identifiers
AliasesCRELD1, AVSD2, CIRRIN, cysteine rich with EGF like domains 1
External IDsOMIM: 607170; MGI: 2152539; GeneCards: CRELD1
Enzyme activity
EC #BRENDAExPASyKEGGMetaCyc
5.3.4.1↗↗↗↗
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez

78987

171508

Ensembl

ENSG00000163703

ENSMUSG00000030284

UniProt

Q96HD1

Q91XD7

RefSeq (mRNA)

NM_001031717
NM_001077415
NM_015513

NM_133930

RefSeq (protein)

NP_598691

Location (UCSC)Chr 3: 9.93 – 9.95 MbChr 6: 113.46 – 113.47 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cysteine-rich with EGF-like domain protein 1 is a protein that in humans is encoded by the CRELD1 gene.[5][6][7]

Function

Epidermal growth factor (EGF)-like repeats are a class of cysteine-rich domains that mediate interactions between proteins of diverse function. EGF domains are found in proteins that are either completely secreted or have transmembrane regions that tether the protein to the cell surface. CRELD1 is the founding member of a family of matricellular proteins.[7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000163703 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030284 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Green EK, Priestley MD, Waters J, Maliszewska C, Latif F, Maher ER (Sep 2000). "Detailed mapping of a congenital heart disease gene in chromosome 3p25". J Med Genet. 37 (8): 581–7. doi:10.1136/jmg.37.8.581. PMC 1734659. PMID 10922384.
  6. ^ Rupp PA, Fouad GT, Egelston CA, Reifsteck CA, Olson SB, Knosp WM, Glanville RW, Thornburg KL, Robinson SW, Maslen CL (Jul 2002). "Identification, genomic organization and mRNA expression of CRELD1, the founding member of a unique family of matricellular proteins". Gene. 293 (1–2): 47–57. doi:10.1016/S0378-1119(02)00696-0. PMID 12137942.
  7. ^ a b "Entrez Gene: CRELD1 cysteine-rich with EGF-like domains 1".

Further reading


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