Born in Florida, Buenos Aires, Lizio came through the youth ranks of River Plate, making his official debut on 10 November 2007 against Huracán in a 2–1 away loss, playing the entire game. His second appearance for the team was in a 2–0 defeat against Banfield on 8 December. The next season, Lizio won the 2008 Clausura Tournament under Diego Simeone. It was his first professional title, despite not making an appearance in the competition.
After a season, he had more chances to play when Néstor Gorosito took over. He made his first appearance under Gorosito in a 2–0 away victory over Independiente at the Estadio Monumental Antonio Vespucio Liberti. His second appearance was when he came off the bench in the 82nd minute in place of Cristian Fabbiani, playing only eight minutes in the match.
Al-Arabi
On 30 June 2013, Lizio signed for Al-Arabi. He left after 3 months with the club.
O'Higgins
In 2014, Lizio joined Chilean side O'Higgins for the 2014–15 season.[1]
Persebaya Surabaya
On 20 February 2019, Lizio is signed by Persebaya Surabaya for the 2019 season. He signed a one-year contract with the club.[2]
Royal Pari
In January 2020, Lizio returned to Bolivia and joined Royal Pari.[3]
In 2014, Lizio accepted to play for the Bolivian national team and made his debut in a non-unofficial FIFA friendly on 13 October against the Brazilian under-23s at Cuiabá, where he scored his side's goal in a 3–1 defeat.[4] On 18 November 2014, he scored his first goal in a 3–2 friendly home win over Venezuela.