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In chemistry, dimerization is the process of joining two identical or similar molecular entities by bonds. The resulting bonds can be either strong or...

Carbene dimerization is a type of organic reaction in which two carbene or carbenoid precursors react in a formal dimerization to an alkene. This reaction...

The telomerization is the linear dimerization of 1,3-dienes with simultaneous addition of a nucleophile in a catalytic reaction. The reaction was independently...

protein NEMO. Some proteins contain specialized domains to ensure dimerization (dimerization domains) and specificity. The G protein-coupled cannabinoid receptors...

formula BH 3. Because it tends to dimerize or form adducts, borane is very rarely observed. It normally dimerizes to diborane in the absence of other...

produced within the Madagascar periwinkle plant (Catharanthus roseus) whose dimerization produces the anti-cancer drugs vinblastine and vincristine. The precursor...

DNA binding domain via a “light switch” mechanism. This allows AraC to dimerize and bind the I1 and I2 operators. The AraC-arabinose dimer at this site...

Ribulose-1,5-bisphosphate carboxylase/oxygenase, commonly known by the abbreviations RuBisCo, rubisco, RuBPCase, or RuBPco, is an enzyme (EC 4.1.1.39)...

(64PPs), their Dewar valence isomers, and the spore photoproduct (SP). Dimerization may proceed via a direct mechanism, in which UV radiation is absorbed...

MAX dimerization protein MGA is a protein that in humans is encoded by the MGA gene. GRCh38: Ensembl release 89: ENSG00000174197 – Ensembl, May 2017 GRCm38:...

called a "epidermal growth factor receptor (HER) dimerization inhibitor" — it inhibits the dimerization of HER2 with other HER receptors, which prevents...

{red}{\ce {H -}}}{\ce {CH2-CH(Ph)}}{\color {red}{\ce {-CH=CH2}}}} The dimerization of ethylene which gives 1-butene is another example of a hydrovinylation...

The parent cyclopentadienone is rarely encountered, because it rapidly dimerizes. Many substituted derivatives are known, notably tetraphenylcyclopentadienone...

chemically induced dimerization applications. FK1012 is a chemical inducer of dimerization (CID) which makes the protein capable of dimerization or oligomerization...

example of a distillable aldol (3-hydroxyaldehyde). Upon standing, it dimerizes reversibly to the dioxane derivative. Hydroxypivaldehyde is a precursor...

binding properties and the leucine zipper that is required to hold together (dimerize) two DNA binding regions. The DNA binding region comprises a number of...

dimerization (CID) is a biological mechanism in which two proteins bind only in the presence of a certain small molecule, enzyme or other dimerizing agent...

metalated intermediate before forming 1,3-cyclobutadiene, which can then dimerize to form the syn-diene. Hydrogenation of the double bonds will form the...

→ (CH3)2C=C=O + Et3NHCl 2 (CH3)2C=C=O → (CH3)2C)2(C=O)2 Ketene itself dimerizes mainly to give the lactone called diketene as well as a small amount of...

C-terminal dimerization subdomain determines dimerization propensity with other proteins in the NF-κB/Rel protein family. The dimerization subdomain is...

acid catalyst. Dimerization unit converts olefins into higher-octane gasoline blending components. For example, butenes can be dimerized into isooctene...

In enzymology, catechol oxidase (dimerizing) (EC 1.1.3.14) is an enzyme that catalyzes the chemical reaction Four catechol   3 O2 6 H2O 3 O2 6 H2O   Two...

colorless liquid. Together with 2,3-dimethyl-2-butene it can be produced by dimerization of propylene. It is a precursor to the commercial fragrance tonalide...

ortho-Carborane is the organoboron compound with the formula C2B10H12. The prefix ortho is derived from the ortho- prefix used to signify that two substituents...

double-stranded RNA binding domain (dsRBD) 3 and 4, 2) the two staufen particles dimerizes by establishing non-covalent interactions between their staufen-swapping...

specifically by the cyclic-GMP-AMP synthase (cGAS). Upon DNA recognition, cGAS dimerizes and stimulates the formation of cyclic-GMP-AMP (cGAMP). cGAMP then binds...

and H. NKG2D is an activating receptor on the NK cell surface. NKG2A dimerizes with CD94 to make an inhibitory receptor (CD94/NKG2A). IPH2201 is a monoclonal...

Jun dimerization protein 2 (JUNDM2) is a protein that in humans is encoded by the JDP2 gene. The Jun dimerization protein is a member of the AP-1 family...

behavior of conventional alkenes such as ethylene. Tetrafluoroethylene dimerizes, giving octafluorocyclobutane. Even normal alkenes and dienes add tetrafluoroethylene...

2-Methylene glutaronitrile is a dimerization product of acrylonitrile and a starting material for di- and triamines, for the biocide...

a strong and unpleasant odor. At room temperature, this cyclic diene dimerizes over the course of hours to give dicyclopentadiene via a Diels–Alder reaction...

It exists in dilute gases, but in a more concentrated form it readily dimerizes to ethane. It is routinely produced by various enzymes of the radical...

reacts with liquid ozone to form a hydrogen superoxide radical, which dimerizes: H + O3 → HO2 + O 2 HO2 → H2O4 Ozone is a toxic substance, commonly found...

the chain is clearly an insulator as the chain is broken into dimers (dimerized). However one of the two cases would consist of N / 2 {\displaystyle N/2}...

the primary dimer initiation site (DIS) as it is believed to promote dimerization of the viral genome through formation of a "kissing dimer" intermediate...

of acid catalysts, ethylene oxide dimerizes to afford dioxane: The reaction mechanism is as follows: The dimerization reaction is unselective. By-products...

cyclopentadiene. The reaction is reversible and at room temperature cyclopentadiene dimerizes over the course of hours to re-form dicyclopentadiene. Cyclopentadiene...

yeast ORC dimerizes in a cell cycle dependent manner to control licensing. [clarification needed] In turn, the process of ORC dimerization is mediated...

component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium...

electrons. Samples of cyclobutadiene are unstable since the compound dimerizes at temperatures above 35 K by a Diels-Alder reaction. By suppressing bimolecular...

pyrolysis of polytetrafluoroethylene (PTFE). Tetrafluoroethylene thermally dimerizes to octafluorocyclobutane, which above 600 °C degrades to hexafluoropropylene...

byproducts resulting from the dimerization of vitamin A. Gildeuretinol is new molecular entity designed to reduce the dimerization of vitamin A in the eye without...

disulfide bonds, and dimerizes under neutral pH and the influence of protein disulfide isomerase A1 (PDIA1).[citation needed] Dimerized pro-VWF is then transported...

could still dimerize, indicating protein-protein interactions were sufficient. However, more recent research has clarified that dimerization is not strictly...

D-domain (Dimerization domain) is found in the upstream of the F-box domain, which is a conserved dimerization motif located in WD40 repeat F box proteins...

has its less stable isomer isocyanogen (cyanogen cyanide), −C≡N+−C≡N. Dimerization of cyanide radicals can also produce a third, even less stable, isomer...

membrane glycoprotein located in the endoplasmic reticulum that also dimerizes and comprises an N‑terminal β‑sandwich‑like domain, a central TIM barrel...

compounds. Single-electron reductants give a deep-blue radical anion, which dimerizes in aqueous solution to the corresponding azo compound and hydrogen peroxide...

catalyzed by solid acid catalysts: C2H4 + H2O → CH3CH2OH Ethylene is dimerized by hydrovinylation to give n-butenes using processes licensed by Lummus...

use of peroxydisulfuric acid gives rise to 1,4‑benzoxazine compounds. Dimerization of isatin with KBH4 in methanol yields Indirubin. This represents the...

presence of catalysts, propylene will form various short oligomers. It can dimerizes to give 2,3-dimethyl-1-butene and/or 2,3-dimethyl-2-butene. or trimerise...

Phosphorylation displaces the disordered R domain from positions preventing NBD dimerization and opening. The amino-terminus is part of the lasso motif which anchors...

57. doi:10.3389/fnins.2014.00057. PMC 4018553. PMID 24834023. OX1–CB1 dimerization was suggested to strongly potentiate orexin receptor signaling, but a...

mutation on the surface of Staphylococcus aureus Sortase A can disrupt its dimerization". Biochemistry. 47 (6): 1667–74. doi:10.1021/bi7014597. PMID 18193895...

alpha helix of a second polypeptide, facilitating dimerization. Leucine zippers are a dimerization motif of the bZIP (Basic-region leucine zipper) class...

bilayer, recognizing the cell surface receptor. Once bound, the F subunit dimerizes with the S subunit to initiate pore assembly. There are exceptions to...

increases the normal boiling point of the compound. Simple carboxylic acids dimerize by forming hydrogen bonds between molecules. A minor factor affecting boiling...

are normally performed in nonpolar media to prevent dimerization.[citation needed] Dimerization of stearic ketene affords alkyl ketene dimers, widely...

reaction, an aldehyde, formed in situ from an alcohol, self-condenses to the dimerized alcohol. Auwers synthesis Aldol addition Klein, David R. (December 22...

compound is chiral although this aspect is not often exploited. Acetaldehyde dimerizes upon treatment with aqueous sodium hydroxide: 2 CH3CHO → CH3CH(OH)CH2CHO...

distinct mutations. Collagen VII is a very large molecule (300 kDa) that dimerizes to form a semicircular looping structure: the anchoring fibril. Anchoring...

Dimer acids, or dimerized fatty acids, are dicarboxylic acids prepared by dimerizing unsaturated fatty acids obtained from tall oil, usually on clay catalysts...

2005). "Design and synthesis of specific probes for human 5-HT4 receptor dimerization studies" (PDF). Journal of Medicinal Chemistry. 48 (20): 6220–6228. doi:10...

similar physical properties. These compounds arise via the acid catalyzed dimerization of isobutene, a reaction that proceeds via the carbocation (CH3)3C+....

presence of acid catalysts. It can also be produced from isobutylene by dimerization using an Amberlyst catalyst to produce a mixture of iso-octenes. Hydrogenation...

ethyl iodide and zinc, but he had not realized that the ethyl radical had dimerized, and thus misidentified the substance. Butane was discovered in crude...

to less-substituted cyclopentadiene derivatives, Cp*H is not prone to dimerization. Pentamethylcyclopentadiene is commercially available. It was first prepared...

The parent cyclobutadiene (R = H) readily dimerizes but the R = tert-butyl derivative is robust....

an antiaromatic one. For this reason, benzocyclobutadiene will readily dimerize or polymerize and it reacts as a dienophile in Diels-Alder reactions. Benzocyclobutadiene...

helical sandwich "filling". Along with the DBD, the LBD contributes to the dimerization interface of the receptor and in addition, binds coactivator and corepressor...

block this dimerization mode. Due to decreasing dimerization energy down Group 14, while monohalogenated stannylenes and plumbylenes dimerize via the halogen-bridging...

C181, the last residue of the stalk region in CD8A, is critical for the dimerization, since it forms an inter-subunit disulfide bond. In CD8αα dimers, it...

receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen-responsive genes. The binding...

irradiation: CF2=CF−CF=CF2 + 2 Br2 → CF2Br−CFBr−CFBr−CF2Br Hexafluorobutadiene dimerizes via a [2+2] process at 150 °C to give perfluorinated divinylcyclobutanes...

interact less, and there is a lower thermodynamic drive for dimerization. In the dimerization reactions, the diene and dienophile were equally electron...

thought to be synthesized by the PR-10 protein Hyp-1 through emodin dimerization, but despite confirming Hyp-1’s structure and ligand-binding capability...

The dimerization partner, RB-like, E2F and multi-vulval class B (DREAM) complex is a protein complex responsible for the regulation of cell cycle-dependent...

chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form...

protein, another protein complex within the SMC protein family. SMC-4 dimerizes with SMC-2, creating the flexible and dynamic structure of the condensin...

or CK5, is a protein that is encoded in humans by the KRT5 gene. It dimerizes with keratin 14 and forms the intermediate filaments (IF) that make up...

mechanism. This butenolide readily dimerizes in aqueous media to form a single cyclodimer. Based on the spontaneous dimerization observed following synthesis...

be designed with cells as their basic components. Chemically induced dimerization systems can be used to make logic gates from individual cells. These...

is involved in retinal, a component of the machinery of vision. The dimerization of alkenes is relevant to the photodamage of DNA, where thymine dimers...

bond at the Rβ-position is converted into a C-OH bond. Additionally, a dimerization reaction has been observed in solutions of freebase methcathinone, which...

they keep the polymerase bound to the DNA. 2 τ units (dnaX) which act to dimerize two of the core enzymes (α, ε, and θ subunits). 1 γ unit (also dnaX) which...

bromine than predicted by the addition reaction. For example, some alkenes dimerize in the presence of bromine. Allylic bromination is another problem. This...

by dimerization of ketene. Heating or irradiation with UV light regenerates the ketene monomer: (C2H2O)2 ⇌ 2 CH2CO Alkylated ketenes also dimerize with...

6b05212. PMID 28168876. Cichewicz RH, Kouzi SA, Hamann MT (January 2000). "Dimerization of resveratrol by the grapevine pathogen Botrytis cinerea". Journal of...

aspartame via enzyme-catalysed amination with phenylalanine. Cinnamic acid can dimerize in non-polar solvents resulting in different linear free energy relationships...

preventing peptidoglycan elongation and cell wall formation. Dalbavancin also dimerizes and anchors itself in the lipophilic bacterial membrane, thereby increasing...

form filamentous polymers in a series of assembly steps beginning with dimerization; dimers assemble into tetramers and octamers and eventually, if the current...

striated muscle; it is a class II myosin with a long coiled coil tail that dimerizes and should not be confused with 'Myosin 1' encoded by the MYO1 family...

cellular transformation. HRI (encoded in humans by the gene EIF2AK1) also dimerizes in order to autophosphorylate and activate. This activation is dependent...

tetrafluoroethylene. This conversion involves pyrolysis to give difluorocarbene, which dimerizes: 2 CHClF2 → C2F4 + 2 HCl The compound also yields difluorocarbene upon...

petrochemical, produced by the catalytic cracking of crude oil or the dimerization of ethylene. Its main uses are in the production of high-octane gasoline...

dependence of the dimerization on substituents. The simple ketene (H2C=C=O) dimerizes to diketene (4-methylen-oxetan-2-one), while substituted ketenes, such...

genetically modified Saccharomyces cerevisiae yeast strains. Farnesene is then dimerized to isosqualene and then hydrogenated to squalane. In olive squalane manufacturing...

finger as lustrous, dark green crystals. Over time, the monomeric material dimerizes to give the parent azobenzene dioxide as a pale yellow solid. As dictated...

"An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation". Nature Structural Biology. 5 (11):...

reaction, is an organic reaction describing (in its original scope) the dimerization or isomerization of electron-deficient alkenes such as enones by action...

explosives (4,4'-Dinitro-3,3'-diazenofuroxan). Furoxanes can be formed by dimerization of nitrile oxides. Clara Cena; Massimo Bertinaria; Donatella Boschi;...

Chenguang; Kielkopf, Clara L; Maquat, Lynne E (April 2013). "Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote...

carbon-halogen bond of the α-haloester by oxidative addition 1. This compound dimerizes and rearranges to form two zinc enolates 2. Unlike lithium enolates and...

nucleotide-binding domain and a C-terminal dimerization domain joined by a long interdomain α-helix. Each protomer's α-helical dimerization domain wraps around the interdomain...

specific" predicted consensus sequence. Additionally, RRM3 contributes to dimerization and oligomerization of HuR, supporting binding to AU-rich elements of...

factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members...

conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is...

Dimerization of lactaldehyde leads to a mixture of stereoisomeric 1,4-dioxanes....

cause carbene insertion. Other reactions include rearrangements and dimerizations. A particular carbene's reactivity depends on the substituents, including...

normally encode for proteins that form dimers to function: MLH1 protein dimerizes with PMS2 protein to form MutLα, which coordinates the binding of other...

It contains a bicyclic aromatic chromophore that is attached to the dimerized cyclic peptide core and a thioacetal bridge. It intercalates into DNA...

in vivo clearance by CYP3A4 ALK-001 (d3-vitamin A) Phase 3 Slows the dimerization rate of vitamin A AVP-786 (d6-dextromethorphan) Phase 3 Reduces formation...

(11 January 2025). "Novel archaeal ribosome dimerization factor facilitating unique 30S-30S dimerization". Nucleic Acids Research. 53 (2) gkae1324. doi:10...

or electron-donating substituents. When irradiated by UV-light, alkenes dimerize to give cyclobutanes. Another example is the Schenck ene reaction, in which...

first (direct) pathway is called transactivation whereby the activated GR dimerizes, is translocated into the nucleus and binds to specific sequences of DNA...

David A.; Aggarwal, Aneel K.; Schildkraut, Ira (September 1998). "Fok I dimerization is required for DNA cleavage". Proceedings of the National Academy of...

heating breaks down into P2 molecules. On cooling, these would normally dimerize to give P4 molecules (i.e. white phosphorus) but, in a vacuum, they link...

Gross, GG (December 2003). "Ellagitannin biosynthesis: Laccase-catalyzed dimerization of tellimagrandin II to cornusiin E in Tellima grandiflora". Phytochemistry...

tendency to form dimers in solution, especially in the presence of oxygen. Dimerization greatly lowers the efficiency of subsequent coupling reactions such as...

necessary for development of the distal segments of the antenna and leg. Ss dimerizes with tango (tgo), which is the homolog to the mammalian Arnt, to initiate...

a09_001. ISBN 3527306730. Blondeau, P.; Berse, C.; Gravel, D. (1967). "Dimerization of an intermediate during the sodium in liquid ammonia reduction of...

N2/CO exchange at atmospheric pressure. Alkylidene ketenes can readily dimerize and participate in cycloaddition reactions. Often orange or red in color...

III parent hydrides exist only under extraordinary conditions. Borane dimerizes irreversibly. Gallane and heavier congeners polymerize, sometimes with...

domain of the HER family of receptors. Those bound proteins then link (dimerize), activating the receptor. HER2 sends a signal from its intracellular domain...

effects on protein expression. The receptors are generally activated by dimerization and substrate presentation. Receptor tyrosine kinases are part of the...

→ [Co(CN)5H]3− + [Co(CN)5OH]3− In concentrated solution, the complex dimerizes: 2[Co(CN)5]3− → [(NC)5Co−Co(CN)5]6− These complexes catalyze the selective...

the Nazarov cyclization reaction and in the Rauhut–Currier reaction (dimerization). When appropriately irradiated, they undergo enone–alkene cycloadditions...

that when α-catenin is not in a molecular complex with β-catenin, it dimerizes and functions to regulate actin filament assembly, possibly by competing...

in the recruitment and activation of the IKKε/TBK-1 complex, inducing dimerization of transcription factors IRF3 and IRF7, which are translocated in the...

Look up Dimer, dimer, dimerization, dimeric, or dimerous in Wiktionary, the free dictionary. Dimer may refer to: Dimer (chemistry), a chemical structure...

groups, and n is the degree of polymerization. One example is the coupled dimerization and hydroesterification of buta-1,3-diene. This step produces a doubly...

cobaltocene, rhodocene does not exist as a monomer, but spontaneously dimerizes by formation of a C–C bond between Cp rings. Co(C5H5)2 is a common one-electron...

activation itself or occurs after activation of individual dimers. EGFR dimerization stimulates its intrinsic intracellular protein-tyrosine kinase activity...

factor activity cytokine activity interleukin-10 receptor binding protein dimerization activity Cellular component extracellular region extracellular space...

an N-terminal dimerization domain. Consisting of an intricate arrangement of α-helices, the rod domain, together with the dimerization-conducting N terminus...

vanadium(III) chloride. This results in a pinacol coupling reaction which dimerizes the material to provide an intermediate which is converted to its epoxide...

the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form...

cation [C6H4(CO2H)(N2)]+. This cation can be used to generate benzyne, dimerized to give diphenic acid, or undergo diazonium coupling reactions such as...

ground state. Unprotected carbene analogs, including germylenes, has a dimerization nature. Free germylenes can be isolated under the stabilization of steric...

are replaced with C–F bonds. Octafluorocyclobutane is produced by the dimerization of tetrafluoroethylene and the reductive coupling of 1,2-dichloro-1,1...

Scott A.; Petsko, Gregory A.; Andersen, Olav M. (January 24, 2023). "Dimerization of the Alzheimer's disease pathogenic receptor SORLA regulates its association...

motif. CLEC7A can induce both Syk dependent or Syk independent pathways. Dimerization of dectin-1 upon ligand binding leads to tyrosine phosphorylation by...

estrogenic. Anethole was demethylated to form anol and anol then spontaneously dimerized into dianol and hexestrol, with DES subsequently being synthesized via...

equilibria can also occur in the gas phase; for example, when nitrogen dioxide dimerizes. 2 NO 2 ↽ − − ⇀ N 2 O 4 {\displaystyle {\ce {2NO2 <=> N2O4}}} ; K p =...

three antiparallel alpha-helices over a twisted antiparallel beta-sheet. Dimerization of ClpS may occur through its N-terminal domain. This short extended...

3-Hydroxybutyraldehyde (acetaldol), an aldol, formally the product of the dimerization of acetaldehyde 4-Hydroxybutyraldehyde, a chemical intermediate Hydroxybutanal...

CYCLE (CYC) (also known as dBMAL for the BMAL1 ortholog in mammals) dimerizes with CLK via their respective PAS domains. This dimer then recruits co-activator...

P, Delic J, Cros S, Paoletti C (1988). "Heterocyclic quinones XIII. Dimerization in the series of 5,8-quinazolinediones: Synthesis and anti tumor effects...

Rapamycin is used in biology research as an agent for chemically induced dimerization. In this application, rapamycin is added to cells expressing two fusion...

forms stable complexes with copper(II) salts. Furoxan may be formed by dimerization of nitrile oxides Olofson, R. A.; Michelman, J. S. (1965). "Furazan"...

prone to dimerization, especially as a free base isolated from plant matter. These dimers are pharmacologically inactive, and the rapid dimerization reduces...

because it has 4n π electrons where n is any integer. For this reason it dimerizes even at temperatures as low as −100 °C. The derivative 1,3,5-tri-tert-butylpentalene...

the DNA-gate and the T-segment is captured. (2) ATP binding stimulates dimerization of the N-gate, the G-segment is cleaved and the T-segment is passed through...

problem with this formulation is "Xe+", which would be a radical and would dimerize or abstract a fluorine atom to give XeF+. Thus, Bartlett discovered that...

membrane bound segments, which indicates either gene duplication or dimerization. The silica deposition that takes place from the membrane bound vesicle...

ATPase domains of GyrB subunits. Binding of 2 ATP molecules leads to dimerization and, therefore, closing of the gates. Hydrolysis, on the contrary, opens...

The Breslow catalytic cycle for formaldehyde dimerization and C2-C6 sugar formation...

p100 into mature p52 subunit in an IKK1/IKKa dependent manner. Then p52 dimerizes with RelB to appear as a nuclear RelB:p52 DNA binding activity. RelB:p52...

change in the PNP pincer ligand leads to a highly regioselective alkyne dimerization catalyst". Chemical Communications (2): 197–199. doi:10.1039/B511148J...

Dimerization of a carboxylic acid....

Dimerization in Ferrimagnetic Chains and Square Lattices", J. Phys. Condensed Matter 12, 9949 (2000). Aiman Al-Omari and A.H. Nayyar, "Dimerization of...

from studies of the Ni-catalyzed linear- and cyclo-dimerization of ethylenes. Linear dimerization proceeds via beta-hydride elimination of the nickelacyclopentane...

membrane, it binds to the GR inducing a conformational change and GC-GR dimerization. It was previously thought that this conformational change was necessary...

or two other molecules of butadiene, i.e., dimerization and trimerization respectively. Via dimerization butadiene is converted to 4-vinylcyclohexene...

alpha-olefins. One class of methods starts with ethylene which is either dimerized or oligomerized. These conversions are respectively effected by the alphabutol...

forms an antiparallel β‑sandwich that contributes to overall stability, dimerization, and correct positioning of the active site. In the human lysosomal isoform...

produced by separation from crude C4 refinery streams and by ethylene dimerization. The former affords a mixture of 1-and 2-butenes, while the latter affords...

case R = CH3CH2, R' = CH3, and R" = H. Such reactions are called aldol dimerization. With a mixture of carbonyl precursors, complicated mixtures can occur...

bulk around the atom bearing the SOMO, the SOMO tends to form a bond by dimerization of the radical. Suppressing this tendency and hence stabilizing the radical...

N-terminal and C-terminal Relish fragments. The N-terminal Relish fragments dimerize leading to their translocation into the nucleus where these dimers bind...

the isobutyric acid or its anhydride into the ketene. This ketene then dimerizes to form a four-membered ring with two ketone groups. The product ring...

phosphorylation recruits STAT transcription factors, predominantly STAT5, which dimerize and migrate to the cell nucleus where they bind to DNA. with an "express...

The systematic name of this enzyme class is glyoxylate carboxy-lyase (dimerizing tartronate-semialdehyde-forming). Other names in common use include tartronate...

An α-formyl aziridine, reduced with DIBAL from the ester, reversibly dimerizes to an oxazolidine: Hydrazines and hydroxylamines displace carbonyl oxygens...

and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner". Molecular and Cellular Biology. 18 (9): 5042–5051. doi:10.1128/mcb...

using a strong acid catalyst. In the NExOCTANE process, isobutylene is dimerized into isooctene and then hydrogenated to isooctane. In World War II, xylidine...

processed in the proteasome and released as a p52 subunit. This subunit dimerizes with RelB and mediates gene expression. In the canonical NF-κB pathway...

double bond rule, most alkyl thioketones are unstable with respect to dimerization. The energy difference between the p orbitals of sulfur and carbon is...

S, Yuan P, Dhar SK, Senga T, Takeda D, Robinson H, et al. (2004). "A dimerized coiled-coil domain and an adjoining part of geminin interact with two...

PMID 1320026. Sundquist, Wesley; Klug, Aaron (1989). "Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops". Nature. 342 (6251):...

The SH2 domains of the STAT5 proteins are once again used for this dimerization. STAT5 can also form homo-tetramers, usually in concert with the histone...

mesenchymal origin. When HGF/SF binds its cognate receptor MET it induces its dimerization through a not yet completely understood mechanism leading to its activation...

others. It belongs to the class of tetrahydroisoquinoline alkaloids. Dimerization of coclaurine leads to the biscoclaurine alkaloids such as cepharanthine...

expression data Gene ontology Molecular function DNA binding protein dimerization activity DNA-binding transcription factor activity DNA-binding transcription...

(FSL-1). After ligand recognition, TLR6 receptor dimerizes with TLR2. Ligand-mediated dimerization is crucial for recruiting the adaptor proteins, which...

Both proteins carry a C-terminus Myb motif and large TERF1-related dimerization domains near their N-terminus. However, both proteins exist exclusively...

transcription repressor activity, RNA polymerase II-specific protein dimerization activity transcription corepressor activity DNA-binding transcription...

the antiaromatic destabilization. Cyclobutadiene, for example, rapidly dimerizes with no potential energy barrier via a 2 + 2 cycloaddition reaction to...

charge from oxygen to nitrogen. Upon condensing to a liquid, nitric oxide dimerizes to colorless dinitrogen dioxide (O=N–N=O), but the association is weak...

parent complex, C5H5FeC6H6, is observed to undergo decomplexation and dimerization, whereas analogues containing six alkyl groups on the benzene ring exhibit...

FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family (e.g., c-Jun, JunD), thereby forming the...

glutamine, which is enzymatically oxidized, cyclized to the heterocycle and dimerized. The names for the segments A, Ox, A, T and Te refer to defined domains...

derives from the aromatic amino acids phenylalanine and tyrosine, via dimerization and oxidative ring-cleavage of arylpyruvic acids, a process that also...

distance, although there is some debate as to its extent. BCl3 does not dimerize, although NMR studies of mixtures of boron trihalides shows the presence...

Is Associated with Aberrant Intermolecular Disulfide Bond Formation (Dimerization) in the Endoplasmic Reticulum". Journal of Biological Chemistry. 277...

apocynin is not understood. In the experimental studies, apocynin is shown to dimerize and form diapocynin. Although, diapocynin seems to have beneficial effect...

of canonical receptor tyrosine kinases such as EGFR leading to their dimerization and subsequent activation of the small GTPase Ras. This then leads to...

electron oxidation generates the triphenylphosphonium radical cation, which dimerizes to the hexaphenyl-1,2-diphosphonium dication [Ph3P–PPh3]2+. Irradiation...

oxidoreductase activity catalytic activity pyridoxal phosphate binding protein dimerization activity glycine binding glycine dehydrogenase (decarboxylating) activity...

membranes through complement activation. The J chain facilitates IgA dimerization by linking two monomer secretory tails. Structurally, the J chain joins...

sulfuric acid, giving the carbocation, which undergoes a variety of dimerization reactions. de Angelis, A.; Ingallina, P.; Perego, C. (2004). "Solid Acid...

precursor to vinylcyclohexene dioxide. It is produced by buta-1,3-diene dimerization in a Diels-Alder reaction. The reaction is conducted at 110 - 425 °C...

Interleukin-6 receptor binds to a second receptor protein, gp130, which thereupon dimerizes and initiates intracellular signaling. The gp130 receptor is present on...

ClCF2−CFCl(I) The latter is a precursor to hexafluorobutadiene. Thermal dimerization of chlorotrifluoroethylene gives 1,2-dichloro-1,2,3,3,4,4-hexafluorocyclobutane...

receptor (EGFR) on the cell surface. This stimulates ligand-induced dimerization, activating the intrinsic protein-tyrosine kinase activity of the receptor...

synthesis is in coupling reactions of alkanes. As an example tert-butanol is dimerized with Fenton's reagent and sulfuric acid to 2,5-dimethyl-2,5-hexanediol...

PMC 362236. PMID 2320002. Hai T, Curran T (May 1991). "Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity"...

efficiently signal via endocannabinoid production to CB1 receptors, dimerization could be an effective way of forming signal complexes with optimal cannabinoid...

defective hormone binding to the ectodomain or reduced efficiency of dimerization of the receptor after hormone occupancy. LS is generally classified as...

process. Several useful structural isomers of the octenes are obtained by dimerization of isobutene and 1-butene. These branched alkenes are used to alkylate...

ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members". Molecular Endocrinology. 12...

Oxidative Cleavage, Stereospecific Epoxidation, Transannulation, and Dimerization". pubs.acs.org. doi:10.1021/acs.jnatprod.5c01426. Retrieved 2026-05-17...

conserved, centrally located, winged helix DNA binding domain as well as a dimerization domain located in the C-terminal region of the sequence. Apart from the...

form appears to be important. Cyanamide dimerizes to give 2-cyanoguanidine (dicyandiamide). This dimerization is hindered or reversed by acids and is...

molecule (such as a rapamycin analog), the binding and signaling proteins dimerize together, allowing the CAR T cells to attack the tumor. Human EGFR truncated...

Bloch W (April 1992). "Prevention of pre-PCR mis-priming and primer dimerization improves low-copy-number amplifications". Nucleic Acids Research. 20...

Lillford PJ (1970). "A Kinetic and Equilibrium Study of Hydrogen Bond Dimerization of 2-Pyridone in Hydrogen Bonding Solvent". J. Am. Chem. Soc. 92 (26):...

stabilize intermolecular contacts. When the (3,5-tBu2H3C6)3CH molecule dimerizes to form [(3,5-tBu2H3C6)3CH]2, stabilizing interactions between tBu groups...

p-xylene or, more readily, the α-substituted derivatives. p-Xylylene dimerizes with moderate efficiency to give p-cyclophane: Further heating of the...

dissociate from the molecular chaperone complexes and become competent to dimerize, migrate to nucleus, and to bind to specific DNA sequences (estrogen response...

via dephosphorylation of BCL-2 which allows pro-apoptotic protein BAX to dimerize and initiate programmed cell death. Mebendazole has also been shown to...

binding ligase activity protein phosphorylated amino acid binding protein dimerization activity beta-catenin binding ubiquitin protein ligase activity ubiquitin-protein...

Halazonetis TD, Georgopoulos K, Greenberg ME, Leder P (December 1988). "c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding...

quantitative yield by oxidation with lead(IV) acetate, which rapidly dimerizes to biphenylene in good yields. Electron deficient heterocycles, such as...

due to their enhanced sequence specificity. ZFN work in pairs, their dimerization being mediated in-situ through the FokI domain. Each zinc finger array...

used as a compound of adhesives and oil-based varnishes. When TOFA is dimerized to dimer acid it is used for making polyamide and epoxy resin. DTO is...

"Double Homologation Method for Substituted Soluble Pentacenes and Dimerization Behaviours of Pentacenes". Chemistry: An Asian Journal. 4 (2): 294–301...

conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. That protein cleaves and activates caspases...

(2014-11-17). "Localized light-induced protein dimerization in living cells using a photocaged dimerizer". Nature Communications. 5 (1): 5475. doi:10.1038/ncomms6475...

alkyl) and with free radicals, forming glutathionyl radicals (GS•) that may dimerize to disulfide: GSH + R• → RH + GS• → ⁠1/2⁠ GSSG Thiyl radicals (such as...

Qifan; Liu, Dongdong; Fang, Ting; Shi, Yajie; Du, Yang (2018-01-31). "Dimerization of Aromatic Compounds Using Palladium-Carbon-Catalyzed Suzuki–Miyaura...

disproportionation of formaldehyde (to methanol and formate) occurs. The initial dimerization of formaldehyde to give glycolaldehyde (1) occurs via an unknown mechanism...

geometry with C2v symmetry, much like chromyl chloride. Chromyl fluoride dimerizes via fluoride bridges (as O2Cr(μ-F)4CrO2) in the solid state, crystallizing...

protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the...

ontology Molecular function transcription coactivator activity protein dimerization activity protein binding enzyme binding oxidoreductase activity Cellular...

Dimanganese decacarbonyl, which has the chemical formula Mn2(CO)10, is a binary bimetallic carbonyl complex centered around the first row transition metal...

forms a salt bridge with arginine and a hydrogen bond with glutamine. Dimerization is essential to maintaining function as the active site is found at this...

unfavorable process. cis, trans-1,5-Cyclooctadiene is also believed to undergo dimerization via this mode. Ketenes are a large class of reactants favoring [2 + 2]...

a political party in Turkey Juicy Drop Pop, a brand of lollipops Jun dimerization protein, a member of the AP-1 family of transcription factors J.D. Power...

phosphorylation, and become phosphorylated by JAK's themselves. STATs then dimerize and move to the nucleus to act as transcription factors. The specific genes...

promote cross-coupling a diene to an olefin. Fe(acac)3 catalyzes the dimerization of isoprene to a mixture of 1,5-dimethyl-1,5-cyclooctadiene and 2,5-dimethyl-1...

in X-gal and form galactose and 5-bromo-4-chloro-3-hydroxyindole which dimerizes and oxidizes to 5,5'-dibromo-4,4'-dichloro-indigo, an intense blue product...

palindromic loop that forms a kissing-loop complex between HIV-1 RNA genomes to dimerize them for encapsidation. The transcript begins, at the beginning of R, is...

S2CID 8235923. Assmann EM, Alborghetti MR, Camargo ME, Kobarg J (2006). "FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil...

"super-Sox" − a chimeric transcription factor with enhanced capacity to dimerize with Oct4. The baseline stem cells commonly used in science that are referred...

tyrosine kinase receptors (the VEGFRs) on the cell surface, causing them to dimerize and become activated through transphosphorylation, although to different...

enol silanes through treatment with ceric ammonium nitrate. Oxidative dimerization of aldehydes in the presence of amines proceeds through the formation...

phosphaallenes quickly dimerize in a [2+2]- or [2+3]-cycloaddition to yield four- or five-membered rings. Thus, in order to prevent dimerization, a bulky moiety...

usually an inactive monomer inhibited by ICAD. This is cleaved before dimerization. Apoptosis is a cell self-destruct process that removes toxic and/or...

electroreducing its toluate ester. In concept, adiponitrile is prepared from dimerizing acrylonitrile: 2 CH2=CHCN + 2 e− + 2 H+ → NC(CH2)4CN In practice, the...

to form dimers with other C/EBPs or other transcription factors. This dimerization allows the C/EBPs to bind specifically to DNA through a palindromic sequence...

oligomeric state of PSBD. In each E2 homotrimer, two of the three PSBDs dimerize. While two E1 homodimers cooperatively bind dimeric PSBD, the remaining...

polypeptides contains a two domains: a DNA-binding domain and a dimerization domain. The dimerization domain binds to other LexA polypeptides to form dumbbell...

PMID 25093327. Kronqvist, N.; et al. (2014). "Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk...

pelargonic acid can be produced in a two-step process beginning with coupled dimerization and hydroesterification of 1,3-butadiene. This step produces a doubly...

inhibits cell–cell repulsion and enhances cell–cell contact duration. SRGAP2 dimerizes through its F-BAR domain. SRGAP2C, a shortened version found in early...

MyD88-dependent and TRIF-dependent pathway. The MyD88-dependent response occurs on dimerization of TLRs, and is used by every TLR except TLR3. Its primary effect is...

elemental sulfur. The main route to cyclooctane derivatives involves the dimerization of butadiene, catalysed by nickel(0) complexes such as nickel bis(cyclooctadiene)...

(MeO)3Al The molecule is monomeric, unlike H3B and Et3Al, which tend to dimerize. It has a planar BC3 core. Triethylborane was used to ignite the JP-7 fuel...

(2026). "A Novel Small-Molecule TLR7 Agonist AXC-715 Stabilizes TLR7 Dimerization and Exhibits Broad-Spectrum Antiviral Activity". Microorganisms. 14 (4):...

unsuccessful. The trityl free radical, Ph3C · , was originally thought to dimerize to form hexaphenylethane. However, an inspection of the NMR spectrum of...

The stalks of two KHCs intertwine to form a coiled coil that directs dimerization of the two KHCs. In most cases transported cargo binds to the kinesin...

colorless liquid with a strong odor. 1,5-Cyclooctadiene can be prepared by dimerization of butadiene in the presence of a nickel or iron catalyst, a coproduct...

only contains the extracellular domains D1 and D2. The FGFRs are known to dimerize as heterodimers and homodimers. So far, five distinct membrane FGFR have...

the lab in 2022 to test the proto-ribosome hypothesis. It was able to dimerize and to form peptide bonds. A much shorter RNA molecule has been synthesized...

induces post-transcriptional modification of HIF-1α, allowing HIF-1α to dimerize with HIF-1β to form HIF-1. HIF-1 induces many physiological changes that...

isolated in 1986 and was found to be nonaromatic. Above −50 °C (223 K) it dimerizes by a Diels–Alder reaction. Perchlorofulvalene (C4Cl4C)2 is quite stable...

oxide that was produced is oxidized to nitrogen dioxide, which is then dimerized into nitrogen tetroxide: 2 NO + O2 → 2 NO2 2 NO2 ⇌ N2O4, and the remainder...

known in organic chemistry. [8]annulyne is known to exist but quickly dimerizes or trimerizes; the compound has been trapped as its radical anion and...

the product of this reaction was the expected anol, a highly reactive dimerization product in the mother liquors called dianol was also discovered by Charles...

C-terminus. Once phosphorylated at the receiver domain, the response regulator dimerizes, gains enhanced DNA binding capacity and acts as a transcription factor...

diiodide (IH 2C)2C=CH 2 in the gas phase. However the product quickly dimerizes to yield 1,4-dimethylenecyclohexane, and also 2-methylpropene by abstracting...

is not clearly understood yet but it is hypothesised that it is for dimerization to the cell surface. LAR-RPTP binds to the LRR1 region through its PTPδ...

single calcium ion. The N-terminal domain is also responsible for the dimerization of the protein to form the full glutamate/aspartate carrier. The carrier...

1-hexene. Another commercial process, offered by a technology licensor IFP, dimerizes ethylene to high purity 1-butene. There are two alpha-olefin processes...

DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity Cellular component nucleolus nucleoplasm cytoplasm nucleus PML...

October 2019. Jiang BH, Rue E, Wang GL, Roe R, Semenza GL (July 1996). "Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor...

probes in their truncated form, which may reduce their ability to bind and dimerize. SMiLE-seq enables robust identification of DNA binding specificities of...

"One-Pot Synthesis Benzils from Aldehydes Via NHC-Catalyzed Benzoin Dimerization Under Metal-Free Conditions in Water". Journal of the Chilean Chemical...

adduct formation with Lewis acids. The osmocenium cation [Os(C5H5)2]+ dimerizes, forming a binuclear complex with an Os-Os bond. In contrast, the decamethylosmocenium...

6-sialyltransferase dimer formation. Role of cysteine residues in enzyme dimerization, localization, activity, and processing". The Journal of Biological Chemistry...

Pnma a=13.065 b=22.049 c=10.55.7 Z=4 3047 1.318 yellow; decompose 220°C; dimerizes N(2,6-iPr2C6H3)C(Me)CHC(Me)N(2,6-iPr2C6H3)(HSe)AlSeAl(SeH)N(2,6-iPr2C6H3)C(Me)CHC(Me)N(2...

series of radical reactions, which is used in its dimerization to bipyridines. Radical dimerization of pyridine with elemental sodium or Raney nickel...

bipartite singlets of many photons. Multiparticle singlets, as well as a dimerized phase of two-body singlets appear in antiferromagnatic models in optical...

conserved basic DNA binding domain that binds the E box DNA motif. They dimerize with other HLH containing proteins through an HLH-HLH interaction. There...

reaction with sodium hydroxide (NaOH). Unfortunately, instantaneous dimerization of the resulting phenol produces trace amounts of 2,3,7,8-tetrachlorodibenzo-p-dioxin...

instead. The final domain of note is a Yjef-N C-terminus domain which dimerizes with mRNA and helps create P-bodies around the location of the decapping...

ISSN 0368-1769. de SOUSA, J. B.; HO, S. K. (1960). "Disproportionation and Dimerization of the Benzyloxyl Free Radical in Solution". Nature. 186 (4727): 776–778...

soluble in most organic solvents. It is prepared by the base-catalysed dimerization of diketene. Commonly used organic bases include imidazole, DABCO, and...

trimethylaluminium (Al2Me6), usually feature tetrahedral Al centers formed by dimerization with some alkyl group bridging between both aluminium atoms. They are...

After being incubated to permit DNA repair, the extent of pyrimidine dimerization (which is indicative of DNA damage) was assessed using sensitive primer...

heterodimer with MSH6 to make the human MutSα mismatch repair complex. It also dimerizes with MSH3 to form the MutSβ DNA repair complex. MSH2 is involved in many...

animals and humans. At room temperature, protoanemonin spontaneously dimerizes into the potentially therapeutic compound anemonin, which can then be...

It is an unusual "example of an odd-electron molecule stable toward dimerization" (nitric oxide being another example). ClO2 crystallizes in the orthorhombic...

15227/orgsyn.025.0058. R. Huisgen, P. Otto (1968), "The mechanism of dimerization of dimethylketene", J. Am. Chem. Soc., vol. 90, no. 19, pp. 5342–5343...

signalling which primes integrins. Moreover, talin proteins are able to dimerize and thus are thought to intervene in the clustering of integrin dimers...

thermal displacement reactions that afford α-olefin chains. Above 150 °C, dimerization of the α-olefins occurs. Aluminum hydroxide, the byproduct of the synthesis...

that in humans are encoded from the same MOCS2 gene. These two proteins dimerize to form molybdopterin synthase. Eukaryotic molybdoenzymes use a unique...

acid. Many methods exist for the preparation of cyclobutanes. Alkenes dimerize upon irradiation with UV light, and, in the Norrish-Yang reaction, irradiated...

(CBS) Dicyclohexyl-2-benzothiazolesulfenamide (DCBS) Oxidative dimerization of MBT gives mercaptobenzothiazole disulfide (MBTS), and sulfenamide...

Certain diazo compounds can couple to form alkenes in a formal carbene dimerization reaction. Diazo compounds are intermediates in the Bamford–Stevens reaction...

to (+)-pinoresinol in the presence of a one-electron oxidant through dimerization of stereospecific radical intermediate. Pinoresinol is subsequently reduced...

followed by an alpha-helical domain and a hydrophilic tail. Merlin can dimerize with itself and heterodimerize with other ERM family proteins.[citation...

concentration of the chemokine. CCL5 may act as a monomer or a dimer. Dimerization is not necessary for binding to CCR5. Thus, CCL5 in nanomolar concentration...

group. The C-terminal domain contributes to structural stability and dimerization. Two prominent structural loops, LL1 and LL2, are characteristic of...

dimerize in the presence of FK1012, a derivative of the drug tacrolimus (FK506). This has made it a useful tool for chemically induced dimerization applications...

ectodomains, ED1 to ED3, and a transmembrane segment. ED2 includes the dimerization interface, two glycosylation sites, and the peptide of fusion with the...

whose 3D structure is known, has unique NMR spectra and is stabilized by dimerization and 28 Cα-H··O=C hydrogen bonds. The PPII helix is not common in transmembrane...

57. doi:10.3389/fnins.2014.00057. PMC 4018553. PMID 24834023. OX1–CB1 dimerization was suggested to strongly potentiate orexin receptor signaling, but a...

can be produced conveniently and nearly all are unstable (see: carbene dimerization). An exception are dihalocarbenes such as dichlorocarbene or difluorocarbene...

the kinase catalytic moiety. This HisRS-like region forms a dimer and dimerization is required for GCN2 function. The crucial contribution to GCN2 function...

the first to isolate cyclopropenylidenes, mesoionic carbenes that cannot dimerize, resulting in a relaxation of steric requirements for their isolation More...

(Aug 15, 1995). "Multiple Bcl-2 family members demonstrate selective dimerizations with Bax". Proc. Natl. Acad. Sci. U.S.A. 92 (17): 7834–8. Bibcode:1995PNAS...

protein from Forsythia intermedia, production of (+)-pinoresinol is greatly enriched while production of other products of dimerization is inhibited....

2.0]decapentaene reacts with oxygen in air. When heated to 100 °C it dimerizes by converting to a yellow oil that consists of three eight member unsaturated...

used in pesticide formulations until 1955. Mirex was produced by the dimerization of hexachlorocyclopentadiene in the presence of aluminium chloride. Mirex...

More reference expression data Gene ontology Molecular function protein dimerization activity protein homodimerization activity endopeptidase activity protease...

of Vps27 (vacuolar protein sorting protein 27) and Hse1. Vps27 and Hse1 dimerize through antiparallel coiled-coil GAT (so named after proteins GGA and Tom1)...

steps of the ligase reaction. C-terminal Domain: Contributes to the dimerization interface. The transition from the ligase-competent to the repressor-competent...

M011311200. PMID 11278883. Zhu CC, Cook LB, Hinkle PM (August 2002). "Dimerization and phosphorylation of thyrotropin-releasing hormone receptors are modulated...

has only a fleeting existence under laboratory conditions, otherwise it dimerizes. The substituted derivative tetraphenylcyclopentadienone is however robust...

fingers – with the catalytic domain of the FokI endonuclease which need to dimerize to cleave the double-strand DNA. The two proteins recognize two DNA sequences...

each other. Unlike the parent compound cyclopentadienone, which rapidly dimerizes, the tetraphenyl derivative is isolable at room temperature....

able to form activin heterodimers with βA or βB subunits but is unable to dimerize with inhibin α. Activin is produced in the gonads, pituitary gland, placenta...

monolignols. Thus, most lignans feature a C18 cores, resulting from the dimerization of C9 precursors. The coupling of the lignols occurs at C8. Eight classes...

with retinoid "X" receptors (RXRs; RXRα, RXRβ, RXRγ). RARs and RXRs must dimerize before they can bind to the DNA. Expression of more than 500 genes is responsive...

hexaphenylethane-like structure. For example, the tris(3,5-di-tert-butylphenyl) radical dimerizes to give hexakis(3,5-di-t-butylphenyl)ethane, with a bond length of 1.67 Å...

Gavarini, Nutan Sharma, Laurie J Ozelius, D Cristopher Bragg (2011): Dimerization of the DYT6 dystonia protein, THAP1, requires residues within the coiled-coil...

amino acids long. Current data indicates that this domain allows for dimerization between MLN64 and MENTHO molecules and with themselves. The domain may...

More reference expression data Gene ontology Molecular function protein dimerization activity DNA-binding transcription factor activity DNA-binding transcription...

protein structural motif that characterizes one of the largest families of dimerizing transcription factors. The word "basic" does not refer to complexity but...

→ CH3(CH2=C−C=CH2)CH3 + 2 H2O The current industrial route involves dimerization of propene followed by dehydrogenation. In 1909, Fritz Hofmann and a...

chemotherapeutic agents. c-Myc, a transcription factor, can be inhibited during its dimerization with Max protein by molecules such as IIA6B17 and omomyc. Inhibition...

et al. (2003). "Uroplakin IIIb, a urothelial differentiation marker, dimerizes with uroplakin Ib as an early step of urothelial plaque assembly". J....

by inhibiting MyoD activity through multiple mechanisms. When BHLHE41 dimerizes with MyoD and E47, it prevents the formation of MyoD-E47 heterodimers...

activity primarily occurs in the liver. When growth hormone is bound to two dimerized GH receptors, the shedding activity is inhibited. This occurs because...

David A.; Aggarwal, Aneel K.; Schildkraut, Ira (1 September 1998). "FokI dimerization is required for DNA cleavage". Proceedings of the National Academy of...

octameric quaternary structure, two dimerization types can be seen that in turn, form the octamer structure. Dimerization is an important aspect of protein...

ErbB3 that causes the protrusion of the dimerization loop in subdomain II, activating the protein for dimerization. ErbB3 has been shown to bind the ligands...

β-galactosidase to form 5-bromo-4-chloro-indoxyl, which then spontaneously dimerizes and oxidizes to form a bright blue insoluble pigment 5,5'-dibromo-4,4'-dichloro-indigo...

persistent organic pollutants, to varying degrees. Hexachlorocyclohexane was dimerized to produce mirex, a banned pesticide. Common forms are: alpha-hexachlorocyclohexane...

remedy for hemorrhoids. On drying of these plants, the protoanemonin toxin dimerizes to non-toxic anemonin, which is further hydrolyzed to non-toxic dicarboxylic...

TLR5-flagellin complex: a new mode of pathogen detection, conserved receptor dimerization for signaling". Science Signaling. 5 (216): pe11. doi:10.1126/scisignal...

expression data Gene ontology Molecular function transferase activity protein dimerization activity protein N-terminus binding transcription coactivator activity...

PMEL. UV radiation causes damage to the DNA of cells, typically thymine dimerization, which, when unrepaired, can create mutations in the cell's genes. This...

cofactor and point mutations in the enzyme. A G473D mutation impairs dimerization and catalysis in human sulfite oxidase. Sulfur metabolism Bioinorganic...

receptor heterodimers form in the cytoplasm through alternative dimerization interfaces". Molecular and Cellular Biology. 21 (3): 781–793. doi:10...

1126/science.283.5404.987. PMID 9974392. Ebie AZ, Fleming KG (February 2007). "Dimerization of the erythropoietin receptor transmembrane domain in micelles". Journal...

membranes) and then binds to a Glucocorticoid Receptor (GR). This receptor dimerizes and the cortisol/GR complex passes into the nucleus where it then binds...

Convention on Persistent Organic Pollutants in 2009. Chlordecone is made by dimerizing hexachlorocyclopentadiene and hydrolyzing to a ketone. It is also the...

cells, having unique palindromic sequences and encoding a leucine zipper dimerization motif". Biochemical and Biophysical Research Communications. 243 (2):...

However exposure to the thrombospondin ligand causes CD36 to dimerize. This dimerization has been proposed to play an important role in CD36 signal transduction...

less stable than MSP nanodiscs. Recent studies, however, showed that dimerization and polymerization of the peptides make them more stable. Another way...

each other, and do not operate in a cooperative fashion. Additionally, dimerization of APH(3') does not affect the activity of the enzyme. Each monomer consists...

epsilonN-methyltransferase S-adenosyl-L-methionine:[3-phospho-D-glycerate-carboxy-lyase (dimerizing)]-lysine 6-N-methyltransferase) Methyllysine RuBisCO SET domain Magnani...

the formation of two equivalents of enol radical, which may subsequently dimerize. (3) Treatment of enolates derived from either one- or two-electron reducing...

Stephen; Akhtar, Asifa; Kadlec, Jan (November 2012). "Msl1-Mediated Dimerization of the Dosage Compensation Complex Is Essential for Male X-Chromosome...

Zhang KD, Dai JL, Zhu YY, Zhao X (June 2014). "Encapsulation enhanced dimerization of a series of 4-aryl-N-methylpyridinium derivatives in water: new building...

conditions, by cycloreversion processes. They are also prone to rapid dimerization, acting as dienes or dienophiles in cycloaddition reactions. Benzo-fused...

timescale due to migrations of the silyl substituents over the cage. The dimerization reaction observed for the carbon tetrahedrane compound is also attempted...

have several unique features, including chaperone-free folding and weak dimerization. Cryogenic electron microscopy showed that BtubA/B forms microtubules...

acidic workup. The Kolbe electrolysis is an electrolytic, decarboxylative dimerization reaction. It gets rid of the carboxyl groups of two acid molecules, and...

chromosome Dictyotene Dideoxy method Differentiation Dihybrid Dihybrid cross Dimerization Dimorphism Dioecious plant Diploid Directed evolution Directed mutagenesis...

Binding interaction between NGF and the TrkA receptor facilitates receptor dimerization and tyrosine residue phosphorylation of the cytoplasmic tail by adjacent...

oligomerization and dimerization of conjugated dienes. For example, 1,5-cyclooctadiene and 4-vinylcyclohexene are produced by dimerization of 1,3-butadiene...

tellimagrandin II               casuarictin It is laccase-catalyzed dimerized to cornusiin E in Tellima grandiflora. It has an extremely weak basic...

metalloprotein. Upon steroid binding, many kinds of steroid receptors dimerize: two receptor subunits join together to form one functional DNA-binding...

activate a signaling pathway in an animal with temporal and spatial control. Dimerizer kits have been distributed freely resulting in many peer-reviewed publications...

SMC complex known as MukBEF. MukBEF forms a "dimer-of-dimers" through dimerization mediated by the kleisin subunit MukF (Figure 3, center). The third subunit...

combination of antibodies blocking VEGFR ligand binding and receptor dimerization". Cancer Cell. 18 (6): 630–640. doi:10.1016/j.ccr.2010.11.001. PMID 21130043...

A. J., Cooper, M. A., O'Brien, D. P., Williams, D. H. "The Roles of Dimerization and Membrane Anchoring in Activity of Glycopeptide Antibiotics against...

expression data BioGPS n/a Gene ontology Molecular function protein dimerization activity DNA binding Cellular component nucleus Biological process regulation...

S-adenosyl-L-methionine:(3-phospho-D-glycerate-carboxy-lyase (dimerizing))-lysine 6-N-methyltransferase may refer to: (Ribulose-bisphosphate carboxylase)-lysine...

tropomyosin binding protease binding transmembrane transporter binding protein dimerization activity cysteine-type endopeptidase activity Cellular component cytoplasm...

produced by hydroboration. The lowest borane, BH3 exists only transiently, dimerizing instantly to form diborane, B2H6. Its adduct borane–tetrahydrofuran and...

and 5-bromo-4-chloro-3-hydroxyindole - 1. The latter then spontaneously dimerizes and is oxidized into 5,5'-dibromo-4,4'-dichloro-indigo - 2, an intensely...

first formed the highly reactive intermediate 57, which subsequently dimerized to yield [2,2]paracyclophane 58. Scheme 11. Pericyclic sequence for the...

to viral infection. Aggregated MAVS have been found to activate IRF3 dimerization. A 2015 study shows phosphorylation of innate immune adaptor proteins...

1992). "CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative...

lithium phosphides have also been found to lead to monomers which then dimerize into the diphosphadiboretanes. In 2002, a direct synthesis to a diphosphadiboretanediyl...

Swaminathan, V. N.; Carell, T; Zinth, W; Kohler, B; et al. (2007). "Thymine dimerization in DNA is an ultrafast photoreaction". Science. 315 (5812): 625–629....

much vitamin A in retinoid form can be harmful. The body converts the dimerized form, carotene, into vitamin A as it is needed, so high levels of carotene...

H4 histones first form a heterodimer and then in turn the heterodimer dimerizes to form a tetramer (H3-H4)2. The heterodimer formation is based on the...

Collins AV, Harlos K, Jones EY, et al. (January 2000). "Structure and dimerization of a soluble form of B7-1". Immunity. 12 (1): 51–60. doi:10.1016/s1074-7613(00)80158-2...

induces a conformational change in the receptor that causes receptor dimerization and activation.[citation needed] The binding of ANP to its receptor causes...

PMID 11336703. Zhang Y, Neo SY, Han J, Lin SC (August 2000). "Dimerization choices control the ability of axin and dishevelled to activate c-Jun...

including labile but complexes with some noble gases. Norbornadiene was dimerized photochemically in the presence of Cr(CO)6, similarly to other metal complexes...

proposed to explain transmembrane receptors' mechanism of action. Dimerization: The dimerization model suggests that prior to ligand binding, receptors exist...

3-Triphenyl-2-propyn-1-ol with thionyl chloride. The resulting chloroallene undergoes dimerization and dehydrochlorination to give rubrene. Rubrene, like other polycyclic...

terminus of human herpesvirus 8 latency-associated nuclear antigen mediates dimerization, transcriptional repression, and targeting to nuclear bodies". Journal...

sunscreen and as an antimicrobial agent. It is derived from the oxidative dimerization of homogentisic acid. It has been both widely and falsely reported that...

systematic name of this enzyme class is ATP phosphohydrolase (tubulin-dimerizing). Katanin McNally FJ, Vale RD (1993). "Identification of katanin, an ATPase...

inhibits its own activators. After PER is produced from per mRNA, it dimerizes with Timeless (TIM) and the complex goes into the nucleus and inhibits...

changes following selective phosphorylation, and its redox-sensitive dimerization. However, mounting evidence demonstrated that occludin is not only present...

to regenerate active catalyst is needed in this reaction. Reductive dimerization of electrophiles has long been known (Wurtz reaction, Ullman reaction...

More reference expression data Gene ontology Molecular function protein dimerization activity protein binding lipid binding protein-macromolecule adaptor...

double-stranded RNA binding domain (dsRBD) 3 and 4, 2) the two Staufen particles dimerizes by establishing non-covalent interactions between their Staufen-swapping...

mechanistic behavior. For example, it has been used to study the rate of dimerization of substrates upon electrochemical reduction. In 2013–2014 Atangana et...

et al. (2023). "The SORL1 p. Y1816C variant causes impaired endosomal dimerization and autosomal dominant Alzheimer's disease". medRxiv 10.1101/2023.07...

ions [Cp2Rh]+ are very stable, unlike the neutral monomers Cp2Rh which dimerize immediately at room temperature and they have been observed in matrix isolation...

Cierpicki T, Paduch M, Derewenda ZS, Otlewski J (March 2006). "The dimerization mechanism of LIS1 and its implication for proteins containing the LisH...

steric hindrance at the core of the molecule, as most natural products dimerize and trimerize in a head-to-head fashion rather than head-to-tail. Research...

receptors. Specifically, they discovered that the catalytic subunit p110 dimerizes with the regulatory subunit p85, and that the SH2 domain of p85 specifically...

2015). "Andes virus nucleocapsid protein interrupts protein kinase R dimerization to counteract host interference in viral protein synthesis". Journal...

takes place, the protein precursor folds via a sulfide–sulfide bond and dimerizes. The protein then is modified by N-linked glycosylation during packaging...

component gain promotes cell proliferation and survival unknown MGA MAX dimerization protein ~8% tumor suppressor loss unknown unknown MLL2 MLL2 7–80% histone...

is phosphorylated. This phosphorylation activates Parkin by inducing dimerization, an active state. [citation needed] This allows for Parkin-mediated ubiquitination...

receptor for the stem cell factor (SCF) retains ligand-induced receptor dimerization and antagonizes SCF-stimulated cellular responses". J. Biol. Chem. 267...

higher developmental potential could also be generated by enhancing dimerization between Oct4 and Sox2 using a chimeric Sox factor. Sox family: The Sox...

substrate CN+1 carboxylic acids are observed due to fragmentation and dimerization of carbon monoxide-derived carbenium ions, especially since each step...

PJ, Fourrier C, Chopin P, Valentin JP, John GW, et al. (March 1998). "Dimerization of sumatriptan as an efficient way to design a potent, centrally and...

transcription activator activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA...

(2019-02-19). "Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM". Proceedings of the National Academy of Sciences...

argument for the occurrence of the Peierls transition, sometimes called dimerization. The earliest written record of the Peierls transition was presented...

interaction of the N- and C- terminals) and a hinge domain that allows dimerization of SMCs. The head and the hinge domains are connected to each other via...

their high degree of toxicity to proliferating cells.[citation needed] Dimerization consists of the bonding of two monomers to form an oligomer, such as...

high disorder. Some proteins in this class function as monomers, but dimerization or higher-order oligomerization is common. The number of single-pass...

and Cycle (CYC) proteins form a heterodimer via the PAS domain. Upon dimerizing, the two proteins bind to the E box promoter element of the two genes...

receptor heterodimers form in the cytoplasm through alternative dimerization interfaces". Molecular and Cellular Biology. 21 (3): 781–93. doi:10.1128/MCB...

PDZ-ligand complex reveals a class I PDZ interaction and a novel PDZ-PDZ dimerization". The Journal of Biological Chemistry. 278 (48): 48099–48104. doi:10...

Eckert D, Bass B (2006). "RDE-4 preferentially binds long dsRNA and its dimerization is necessary for cleavage of dsRNA to siRNA". RNA. 12 (5): 807–18. doi:10...

regulatory subunit of cyclin-dependent kinases CDK4 and CDK6. The protein dimerizes with CDK4/6 to regulate the G1/S phase transition and entry into the S-phase...

allows rapid and tight regulation of the enzyme. Activation involves dimerization and often oligomerisation of pro-caspases, followed by cleavage into...

Urizar E, Lambert NA, et al. (March 2011). "Making structural sense of dimerization interfaces of delta opioid receptor homodimers". Biochemistry. 50 (10):...

variety of products. It is alkylated with butane to produce isooctane or dimerized to diisobutylene (DIB) and then hydrogenated to make isooctane, a fuel...

bent. Without stabilizing ligands, the Cp2ZrII fragment is unstable and dimerizes to form a fulvalene complex. In 1954, Wilkinson and Birmingham described...

S2CID 38527914. L. T. Chong; C. D. Snow; Y. M. Rhee; V. S. Pande. (2004). "Dimerization of the p53 Oligomerization Domain: Identification of a Folding Nucleus...

. {\displaystyle i=1-\left(1-{\frac {1}{n}}\right)\alpha .} For the dimerization of acetic acid in benzene: 2 CH3COOH ⇌ (CH3COOH)2 2 moles of acetic acid...

is composed of an α-helix that forms a "coiled coil" structure when it dimerizes. Members of the C/EBP family can form homodimers or heterodimers with...

overturned by compensation mechanisms. In the case of HER2, which acts as a dimerization partner of other epidermal growth factor receptors (EGFR), constitutive...

expression data BioGPS n/a Gene ontology Molecular function protein dimerization activity Cellular component nuclear membrane integral component of membrane...

become degraded and therefore coalesce and precipitate. However, upon dimerization of alkaline phosphatase, the bonds maintaining its secondary and tertiary...

tris(silox)tantalum to form an unstable tetrahedral intermediate, which quickly dimerizes. Then, the cleavage of the four-membered ring as shown in the diagram...

structure are known. The biosynthesis of terphenylquinones is carried out by dimerization of substituted oxophenylpropanoic acids (phenylpyruvic acids). Terphenylquinones...

PMID 16946301. Lagane B, Chow KY, Balabanian K, et al. (July 2008). "CXCR4 dimerization and beta-arrestin-mediated signaling account for the enhanced chemotaxis...

is the beta sheet, leading researchers to hypothesize the presence of dimerization domains within ICAM-1. The protein encoded by this gene is a type of...

elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is...

(2006-03-01). "Molecular Mechanism for the Regulation of Rho-Kinase by Dimerization and Its Inhibition by Fasudil". Structure. 14 (3): 589–600. doi:10.1016/j...

transcription factor Max (see image at left), which uses a helical coiled coil to dimerize, positioning another pair of helices for interaction in two successive...

subdomains of the EphA3 receptor mediate ligand binding and receptor dimerization". J. Biol. Chem. 273 (32): 20228–37. doi:10.1074/jbc.273.32.20228. PMID 9685371...

hydroxide. Another preparation, performed by Liebig in 1838, is the dimerization of benzaldehyde, to benzil, which is transformed to the product by the...

Although such compounds are not intrinsically unstable, they instead tend to dimerize or even polymerize. Moreover, the multiple bonds of the elements with n=2...

(August 1995). "Multiple Bcl-2 family members demonstrate selective dimerizations with Bax". Proceedings of the National Academy of Sciences of the United...

formation by using light-sensitive 'caged' dimerizers. In this case, light-activation removes the dimerizer cage, allowing it to recruit IDRs to multivalent...

function DNA binding core promoter sequence-specific DNA binding protein dimerization activity DNA-binding transcription activator activity, RNA polymerase...

falls (hypoxia). The protein contains a basic helix–loop–helix protein dimerization domain as well as a domain found in signal transduction proteins which...

membrane-anchored growth factor as well. When TGF-α binds to EGFR it dimerizes triggering phosphorylation of a protein-tyrosine kinase. The activity...

Milatovich A, Mendel DB, Crabtree GR, Francke U (April 1993). "Genes for the dimerization cofactor of hepatocyte nuclear factor-1 alpha (DCOH) are on human and...

from top): Beta scission to give either an acid chloride or ketone. Dimerization to give a peroxide cross-link. Hydrogen abstraction followed by loss...

indole alkaloids are known. They are produced in living organisms through dimerization of monomeric indole bases, in the following reactions: Mannich reaction...

John C. Stowell (1971). "tert-Alkylnitroso compounds. Synthesis and dimerization equilibriums". J. Org. Chem. 36 (20): 3055–3056. doi:10.1021/jo00819a038...

allows BB binding while inhibiting proliferation by impairing receptor dimerization". J. Biol. Chem. 272 (28): 17400–17404. doi:10.1074/jbc.272.28.17400...

accessible by weakly basic hydrolysis of chlorotrimethylsilane, since the dimerization can thus be avoided. Trimethylsilanol can also be obtained by the basic...

is the prototypical thioketone. Unlike other thioketones that tend to dimerize to form rings and polymers, thiobenzophenone is quite stable, although...

protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine...

Krebs cycle intermediates aconitic and isocitric acids. Maleic anhydride dimerizes in a photochemical reaction to form cyclobutane tetracarboxylic dianhydride...

2021). "Targeting the HuR Oncogenic Role with a New Class of Cytoplasmic Dimerization Inhibitors". Cancer Research. 81 (8): 2220–2233. doi:10.1158/0008-5472...

F; Darnell Jr, J. E.; Kuriyan, J (2003). "A reinterpretation of the dimerization interface of the N-terminal Domains of STATs". Protein Science. 12 (2):...

reversibly to nitrite (NO−2) and nitroxyl (HNO). The resulting nitroxyl dimerizes rapidly to hyponitrous acid (HON=NOH), which dehydrates to nitrous oxide...

insulin, for example). It is a ~130 kDa protein that exists mainly in its dimerized or tetramerized forms. α-latrotoxin (α-LTX) can naturally be found in...

sequences RNAcofold Calculate secondary structures of two RNAs with dimerization RNAdistance Calculate distances between RNA secondary structures RNAduplex...

"Effect of carbonyl cyanide m-chlorophenylhydrazone (CCmCP) on the dimerization of lipoprotein lipase". Biochimica et Biophysica Acta (BBA) - Lipids...

dimerization interaction. Experimentally, it has been seen that, in vivo, mutating the Dimerization initiation site (DIS) obstructed the dimerization...

from the pro-region by proteolytic cleavage. The mature TGF-β protein dimerizes to produce a 25 KDa active protein with many conserved structural motifs...

hydrolyzes the indican, releasing β-D-glucose and indoxyl. The indoxyl dimerizes in the mixture, and after 12–15 hours of fermentation yields the yellow...

apoptosome complex, forming a holoenzyme. Activation occurs when caspase-9 dimerizes, and there are two different ways for which this can occur: Caspase-9...

upon by StaD to form an uncharacterized intermediate proposed to be the dimerization product between 2 imine molecules. Chromopyrrolic acid is the molecule...

exists an inverse correlation between the propensity of the CNBH domains to dimerize and the ability of CNNMs to mediate Mg2+ efflux, which has been proved...

Interferon gamma (IFN-γ) is a family of dimerized soluble cytokines in the type II class of interferons. In humans, IFN-γ is the only type II family and...

Pleiadene generation and dimerization...

butadiene followed by oxidative dehydrogenation. The acid-catalyzed dimerization of styrene to give a 1,3-diphenylbutene, which then can be transformed...

PMID 11921171. Zipper LM, Mulcahy RT (September 2002). "The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm". The Journal of...

DNA is that derived from the heterodimer: AP3 and PI, or DEF and GLO, dimerize. This is the form in which they are able to function. The GLO/PI lines...

of these two angiogenic growth factors. Though sFlt-1 can effectively dimerize, its lack of a kinase domain means that no tyrosine phosphorylation occurs...

to interact with a specific PAMP. TLRs tend to dimerize, TLR4 forms homodimers, and TLR6 can dimerize with either TLR1 or TLR2. Interaction of TLRs with...

Jeffrey D. (April 1970). "Kinetics of aqueous indium(III) perchlorate dimerization". The Journal of Physical Chemistry. 74 (9): 1825–1828. doi:10.1021/j100704a001...

interaction with other transcription factors (e.g., homo- or hetero-dimerization) interacting with coregulatory proteins such as co-activators (e.g.,...

PMC 10318606. PMID 37348461. "Contextual computation by competitive protein dimerization networks". Cell. 188 (7). Bintu, Lacramioara; Yong, John; Antebi, Yaron...

H-NS is characterized by an N-terminal domain (NTD) consisting of two dimerization sites, a linker region that is unstructured and a C-terminal domain (CTD)...

localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription...

properties and stability of condensates: for example, UV‑induced thymine dimerization within DNA‑based condensates alters their mechanochemistry and fusion...

typically used as the cleavage domain in ZFNs. This cleavage domain must dimerize in order to cleave DNA and thus a pair of ZFNs are required to target non-palindromic...

PMID 26860303. Sundquist WI, Klug A (December 1989). "Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops". Nature. 342 (6251):...

expression data Gene ontology Molecular function DNA binding protein dimerization activity DNA-binding transcription factor activity chromatin binding...

W. (2004). "Spin Singlet Formation inMgTi2O4: Evidence of a Helical Dimerization Pattern". Physical Review Letters. 92 (5) 056402. arXiv:cond-mat/0308101...

due to their enhanced sequence specificity. ZFN work in pairs, their dimerization being mediated in-situ through the FoKI domain. Each zinc finger array...

dimer between procaspases, which generates a conformational change. This dimerization is essential to create the active site; a p12 subunit is liberated and...

Horejsi V, Strominger JL (December 2002). "Disulfide bond-mediated dimerization of HLA-G on the cell surface". Proc. Natl. Acad. Sci. U.S.A. 99 (25):...

center of cyclopentanone. Hydrolysis liberates the alkynyl alcohol. The dimerization of acetylene to vinylacetylene proceeds by insertion of acetylene into...

dehydrohalogenation of 1,3-dichloro-2-butene Cl−CH2−CH=CCl−CH3. It also arises via the dimerization of acetylene, which is catalyzed by copper(I) chloride. Dehydrogenation...

of the resultant β-ketoacid yields a tricyclic ketone. Oxidation and dimerization yields the completed natural product. Three scytonemin biosynthetic enzymes...

thumbnail). Depending on conditions, such as pH, these dimers can themselves dimerize to form tetramers. Each monomer in the complex has a substrate binding...

"Activation of MTK1/MEKK4 by GADD45 through induced N-C dissociation and dimerization-mediated trans autophosphorylation of the MTK1 kinase domain". Molecular...

(k at 298 K = 8×106 M s): 2 HNO → N2O + H2O The reaction proceeds via dimerization to hyponitrous acid, H2N2O2, which subsequently undergoes dehydration...

(June 2008). "Structural properties of AMP-activated protein kinase: dimerization, molecular shape, and changes upon ligand binding". The Journal of Biological...

PMID 26860303. Sundquist WI, Klug A (December 1989). "Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops". Nature. 342 (6251):...

essentially a dimeric structure. Each monomeric unit has a catalytic core, a dimerization subunit, and a processivity component . DNA Pol III uses one set of its...

Chen H, Yang S, He F (August 2002). "Identification of hepatopoietin dimerization, its interacting regions and alternative splicing of its transcription"...

expression data Gene ontology Molecular function DNA binding protein dimerization activity protein homodimerization activity DNA-binding transcription...

receiver domain (D1). Phosphorylation of the receiver domain increases the dimerization affinity by approximately 10-fold over non-phosphorylated domains. Inhibition...