Discodermia

Discodermia
Discodermia ramifera
Scientific classification Edit this classification
Kingdom: Animalia
Phylum: Porifera
Class: Demospongiae
Order: Tetractinellida
Family: Theonellidae
Genus: Discodermia
du Bocage, 1869[1]
Synonyms
  • Collinella Schmidt, 1879
  • Desmahabana Alcolado & Gotera, 1986

Discodermia is a genus of deep-water sea sponge.[1][2]

Species

The following species are accepted within Discodermia:[1]

Pharmacology

Discodermins B-D

D. dissoluta is of interest to bio and organic chemists because it produces (+)-discodermolide, a polyketide natural product with immunosuppressive and cancer killing properties.[3]

Antimicrobial/anticancer peptides called discodermins have been isolated from D. kiiensis.[4]

References

  1. ^ a b c "Discodermia". WoRMS. World Register of Marine Species. Retrieved 12 Sep 2020.
  2. ^ Brück WM, Sennett SH, Pomponi SA, Willenz P, McCarthy PJ (2008). "Identification of the bacterial symbiont Entotheonella sp. in the mesohyl of the marine sponge Discodermia sp". The ISME Journal. 2 (3): 335–339. Bibcode:2008ISMEJ...2..335B. doi:10.1038/ismej.2007.91. PMID 18256706.
  3. ^ Singh R, Sharma M, Joshi P, Rawat DS (2008). "Clinical status of anti-cancer agents derived from marine sources". Anti-Cancer Agents in Medicinal Chemistry. 8 (6): 603–617. doi:10.2174/187152008785133074. PMID 18690825.
  4. ^ Otero-González, AJ; Magalhaes, BS; Garcia-Villarino, M; Lopez-Abarrategui, C; Sousa, DA; Dias, SC; Franco, OL (2010). "Antimicrobial peptides from marine invertebrates as a new frontier for microbial infection control". FASEB Journal. 24 (5): 1320–34. doi:10.1096/fj.09-143388. PMID 20065108. S2CID 23976702.


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