Draft:LiveSpo

LiveSpo

LiveSpo Pharma
TypePrivate
IndustryBiotechnology, Pharmaceuticals, Probiotics
Founded2010 (as ANABIO R&D)[1]
FounderNguyen Hoa Anh
HeadquartersHanoi, Vietnam
Key people
Nguyen Hoa Anh (Founder & Chairman)
ProductsLiveSpo NAVAX, LiveSpo CLAUSY, LiveSpo DIA30
ServicesR&D, Manufacturing, Distribution
Websitelivespo.com

LiveSpo (also operating as LiveSpo Pharma) is a Vietnamese biotechnology company. Its activities center on the research, development, and manufacturing of spore-based probiotic products delivered in liquid form.[2] The company's technology utilizes high concentrations of multi-strain Bacillus spores in a liquid suspension.[3]

History and Corporate Affairs

LiveSpo was established by Dr. Nguyen Hoa Anh in 2010 under the name ANABIO R&D.[2] The company developed its Spores Probiotics Technology for liquid spore production and began exporting its products by 2014.[2]

Investment and Expansion

In 2021, the company secured an $8.8 million investment from Mekong Capital's Mekong Enterprise Fund IV (MEF IV). The funding was designated to support domestic growth in Vietnam and to facilitate its international expansion, including establishing online sales channels in North America and Europe via platforms such as Amazon.com.[1][2]

Following this capital injection, LiveSpo expanded the national distribution of its products across major pharmaceutical chains in Vietnam.[4]

Scientific Research and Products

ANABIO R&D, the company’s research and development arm, documents its clinical validation studies through peer-reviewed platforms and publications, including Scientific Reports (a journal within the Nature Portfolio).[5]

Published Clinical Trials (Scientific Reports)

The nasal-spray probiotic LiveSpo NAVAX (formulated with Bacillus subtilis and B. clausii spores) has been assessed in several randomized, controlled clinical trials published in Scientific Reports.

Influenza and Acute Respiratory Tract Infections (ARTIs): A 2023 trial involving children with influenza virus infection reported that the application of LiveSpo NAVAX shortened the recovery duration. Relative to the control group, the treatment was associated with a 26-fold reduction in viral load and a 65-fold reduction in bacterial co-infection concentrations.[5]

Acute Rhinosinusitis (ARS) and Otitis Media (AOM): A 2025 trial focusing on pediatric ARS and AOM found that participants receiving LiveSpo NAVAX experienced a 68% reduction in nasal congestion by day 3 and a 97% reduction in rhinorrhea by day 7. These improvements were approximately double the rates observed in the control group.[6][7]

Respiratory Syncytial Virus (RSV): Earlier results from a 2022 trial on children with RSV pneumonia and bacterial co-infection indicated that the nasal-spraying probiotic reduced the required period of oxygen therapy by two days and overall treatment by one day, while treatment effectiveness increased by 58%.[8]

Registered Clinical Trials (ClinicalTrials.gov)

ANABIO R&D is the sponsor of several clinical trials registered on the U.S. National Institutes of Health (NIH) ClinicalTrials.gov platform, investigating the following applications:

LiveSpo COLON for supportive treatment of chronic Inflammatory Bowel Disease (IBD).[9]

LiveSpo X-SECRET for supportive treatment of Vaginitis.[10]

LiveSpo X-SECRET for supportive treatment of Sexually Transmitted Infections (STIs).[11]

References

  1. ^ a b "Mekong Capital invests in fast-growing healthcare firm". Hanoi Times. July 13, 2021.
  2. ^ "A Future Without Antibiotics – The crazy mission of LiveSpo". Mekong Capital Blog. February 20, 2024.
  3. ^ "Mekong Capital - Most Experienced Private Equity Firm in Vietnam". Mekong Capital. October 28, 2025.
  4. ^ a b "Efficient symptomatic treatment and viral load reduction for children with influenza virus infection by nasal-spraying Bacillus spore probiotics". Scientific Reports. National Institutes of Health (NIH) - PMC. September 8, 2023.
  5. ^ "Alleviating symptoms of paediatric acute rhinosinusitis and acute otitis media with otorrhea using nasal-spraying Bacillus probiotics: a randomized controlled trial". ResearchGate (reporting Scientific Reports content). January 18, 2025.
  6. ^ "Alleviating symptoms of paediatric acute rhinosinusitis and acute otitis media with otorrhea using nasal-spraying Bacillus probiotics: a randomized controlled trial". Scientific Reports. PubMed. January 27, 2025.
  7. ^ "Diagram showing the NCT053773452 clinical trial design and data analysis from December 2020 to April 2022". ResearchGate (reporting Scientific Reports content). September 8, 2023.
  8. ^ "Efficacy of LiveSpo COLON as a Supportive Treatment for Inflammatory Bowel Disease (IBD)". ClinicalTrials.gov. October 15, 2024.
  9. ^ "Effects of LiveSpo X-SECRET in Supportive Treatment of Vaginitis". ClinicalTrials.gov. December 11, 2023.
  10. ^ "Effects of LiveSpo X-secret in Supporting Treatment of Sexually Transmitted Diseases". ClinicalTrials.gov. December 11, 2023.

Category:Biotechnology companies Category:Pharmaceutical companies of Vietnam Category:Companies established in 2010

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