Draft:TNMpilot

  • Comment: Can you find independent coverage on its features, use cases, etc? Ca talk to me! 01:37, 24 April 2026 (UTC)
  • Comment: We need independent sources, and there are none here. Stuartyeates (talk) 19:08, 29 January 2026 (UTC)
TNMplot.com
Type of site
Web-based bioinformatics platform
Available inEnglish
Created byÁdám Bartha; Balázs Győrffy
URLhttps://tnmplot.com
Commercialno
RegistrationNot required
Launched2021

TNMplot.com is a web-based bioinformatics platform for comparing gene expression levels across normal, tumor, and metastatic tissue samples.[1]

Background

The platform was developed at Semmelweis University and launched in 2021.[1] It integrates transcriptomic datasets from public repositories including the Gene Expression Omnibus (GEO), The Cancer Genome Atlas (TCGA), and GTEx to enable comparison of gene expression between normal, primary tumor, and metastatic tissues.[1]

Methodology

TNMplot.com enables statistical comparison of gene expression using non-parametric tests including the Mann–Whitney U test and Kruskal–Wallis test. The platform provides visualization outputs such as boxplots and violin plots for comparative analysis.[1]

Use in independent research

Beyond its original description, TNMplot.com has been applied in independent peer-reviewed cancer research studies.

A study published in Frontiers in Molecular Biosciences used the TNMplot database to evaluate differential expression and prognostic relevance of PGK1 in breast cancer.[2]

A pan-cancer study published in Scientific Reports employed the TNMplot gene expression comparison module in integrative analyses examining tumor progression and biomarker associations.[3]

See also

References

  1. ^ a b c d Bartha, Ádám; Győrffy, Balázs (2021). "TNMplot.com: A web tool for the comparison of gene expression in normal, tumor and metastatic tissues". International Journal of Molecular Sciences. 22 (5): 2622. doi:10.3390/ijms22052622. PMC 7961455. PMID 33807717.
  2. ^ Li, Y. (2021). "Expression Characteristics and Significant Prognostic Values of PGK1 in Breast Cancer". Frontiers in Molecular Biosciences. 8 695420. doi:10.3389/fmolb.2021.695420. PMC 8287903. PMID 34291087.
  3. ^ Li, Dongming (2025-01-02). "Integrative pan-cancer analysis and experiment validation identified GLS as a biomarker in tumor progression, prognosis, immune microenvironment, and immunotherapy". Scientific Reports. 15 (1) 525. Bibcode:2025NatSR..15..525L. doi:10.1038/s41598-024-84916-w. PMC 11696030. PMID 39747578.{{cite journal}}: CS1 maint: unflagged free DOI (link)

Category:Web applications Category:Cancer research

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