Fluoren-9-ol dehydrogenase

In enzymology, a fluoren-9-ol dehydrogenase (EC 1.1.1.256) is an enzyme that catalyzes the chemical reaction

fluoren-9-ol + 2 NAD(P)+ ${\displaystyle \rightleftharpoons }$ fluoren-9-one + 2 NAD(P)H + 2 H⁺

The 3 substrates of this enzyme are fluoren-9-ol, NAD⁺, and NADP⁺, whereas its 4 products are fluoren-9-one, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is fluoren-9-ol:NAD(P)⁺ oxidoreductase. This enzyme participates in fluorene degradation.

• Casellas M, Grifoll M, Bayona JM, Solanas AM (1997). "New metabolites in the degradation of fluorene by Arthrobacter sp strain F101". Appl. Environ. Microbiol. 63 (3): 819–26. PMC 168377. PMID 9055403.
• Grifoll M, Casellas M, Bayona JM, Solanas AM (1992). "Isolation and characterization of a fluorene-degrading bacterium: identification of ring oxidation and ring fission products". Appl. Environ. Microbiol. 58 (9): 2910–7. PMC 183026. PMID 1444405.