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GPRASP1
Identifiers
Aliases	GPRASP1, GASP, GASP-1, GASP1, G protein-coupled receptor associated sorting protein 1
External IDs	OMIM: 300417; MGI: 1917418; GeneCards: GPRASP1
Gene location (Human)
Chr.	X chromosome (human)
End	102,659,083 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	134,704,223 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; Brodmann area 23; ; endothelial cell; ; cerebellar vermis; ; superior frontal gyrus; ; lateral nuclear group of thalamus; ; postcentral gyrus; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; orbitofrontal cortex;
	Top expressed in
	central gray substance of midbrain; ; nucleus of stria terminalis; ; paraventricular nucleus of hypothalamus; ; superior colliculus; ; arcuate nucleus; ; dorsomedial hypothalamic nucleus; ; median eminence; ; suprachiasmatic nucleus; ; habenula; ; ventromedial nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; cytosol;
Biological process	G protein-coupled receptor catabolic process; endosome to lysosome transport;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	9737
	67298
	ENSG00000198932
	ENSMUSG00000043384
	Q5JY77
	Q5U4C1
	NM_014710; NM_001099410; NM_001099411; NM_001184727
	NM_001004359; NM_001005385; NM_026081
	NP_001092880; NP_001092881; NP_001171656; NP_055525
	NP_001004359; NP_001005385; NP_080357
	Wikidata
View/Edit Human	View/Edit Mouse

G-protein coupled receptor-associated sorting protein 1 is a protein that in humans is encoded by the GPRASP1 gene.^[5]^[6]^[7]

Interactions

GPRASP1 (gene) has been shown to interact with Delta Opioid receptor.^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000198932 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000043384 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (October 1997). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 4 (5): 307–13. doi:10.1093/dnares/4.5.307. PMID 9455477.
^ Simonin F, Karcher P, Boeuf JJ, Matifas A, Kieffer BL (May 2004). "Identification of a novel family of G protein-coupled receptor associated sorting proteins". Journal of Neurochemistry. 89 (3): 766–75. doi:10.1111/j.1471-4159.2004.02411.x. PMID 15086532. S2CID 6266231.
^ "Entrez Gene: GPRASP1 G protein-coupled receptor associated sorting protein 1".
^ Whistler JL, Enquist J, Marley A, Fong J, Gladher F, Tsuruda P, Murray SR, Von Zastrow M (July 2002). "Modulation of postendocytic sorting of G protein-coupled receptors". Science. 297 (5581): 615–20. doi:10.1126/science.1073308. PMID 12142540. S2CID 1219372.

Patrie KM, Drescher AJ, Goyal M, Wiggins RC, Margolis B (April 2001). "The membrane-associated guanylate kinase protein MAGI-1 binds megalin and is present in glomerular podocytes". Journal of the American Society of Nephrology. 12 (4): 667–77. doi:10.1681/ASN.V124667. PMID 11274227.
Whistler JL, Enquist J, Marley A, Fong J, Gladher F, Tsuruda P, Murray SR, Von Zastrow M (July 2002). "Modulation of postendocytic sorting of G protein-coupled receptors". Science. 297 (5581): 615–20. doi:10.1126/science.1073308. PMID 12142540. S2CID 1219372.
Heydorn A, Søndergaard BP, Ersbøll B, Holst B, Nielsen FC, Haft CR, Whistler J, Schwartz TW (December 2004). "A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP)". The Journal of Biological Chemistry. 279 (52): 54291–303. doi:10.1074/jbc.M406169200. PMID 15452121.
Bartlett SE, Enquist J, Hopf FW, Lee JH, Gladher F, Kharazia V, Waldhoer M, Mailliard WS, Armstrong R, Bonci A, Whistler JL (August 2005). "Dopamine responsiveness is regulated by targeted sorting of D2 receptors". Proceedings of the National Academy of Sciences of the United States of America. 102 (32): 11521–6. Bibcode:2005PNAS..10211521B. doi:10.1073/pnas.0502418102. PMC 1183554. PMID 16049099.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000198932 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000043384 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9455477-5] Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (October 1997). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 4 (5): 307–13. doi:10.1093/dnares/4.5.307. PMID 9455477.

[pmid15086532-6] Simonin F, Karcher P, Boeuf JJ, Matifas A, Kieffer BL (May 2004). "Identification of a novel family of G protein-coupled receptor associated sorting proteins". Journal of Neurochemistry. 89 (3): 766–75. doi:10.1111/j.1471-4159.2004.02411.x. PMID 15086532. S2CID 6266231.

[entrez-7] "Entrez Gene: GPRASP1 G protein-coupled receptor associated sorting protein 1".

[pmid12142540-8] Whistler JL, Enquist J, Marley A, Fong J, Gladher F, Tsuruda P, Murray SR, Von Zastrow M (July 2002). "Modulation of postendocytic sorting of G protein-coupled receptors". Science. 297 (5581): 615–20. doi:10.1126/science.1073308. PMID 12142540. S2CID 1219372.

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GPRASP1

Interactions

References

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