GPRASP2

GPRASP2

Identifiers

GPRASP2, GASP2, G protein-coupled receptor associated sorting protein 2, DFNX7

External IDs

OMIM: 300969; MGI: 2442071; GeneCards: GPRASP2

Gene location (Human)

Chr.	X chromosome (human)^[1]

Band	Xq22.1	Start	102,712,445 bp^[1]
Band	Xq22.1	End	102,717,733 bp^[1]

Gene location (Mouse)

Chr.	X chromosome (mouse)^[2]

Band	X F1\|X 57.3 cM	Start	134,739,783 bp^[2]
Band	X F1\|X 57.3 cM	End	134,745,479 bp^[2]

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

endothelial cell

Brodmann area 23

middle temporal gyrus

pons

postcentral gyrus

superior vestibular nucleus

cardiac muscle tissue of right atrium

entorhinal cortex

lateral nuclear group of thalamus

superior frontal gyrus

Top expressed in

dorsomedial hypothalamic nucleus

paraventricular nucleus of hypothalamus

arcuate nucleus

ventromedial nucleus

median eminence

lateral hypothalamus

suprachiasmatic nucleus

ventral tegmental area

dorsal tegmental nucleus

central gray substance of midbrain

More reference expression data

n/a

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


114928


245607


ENSG00000158301


ENSMUSG00000072966


Q96D09


Q8BUY8

RefSeq (mRNA)


NM_138437 NM_001004051 NM_001184874 NM_001184875 NM_001184876


NM_001163015 NM_001163016 NM_001163017 NM_001359371

RefSeq (protein)

NP_001186747 NP_001337197 NP_001337198 NP_001337199 NP_001004051
NP_001171803 NP_001171804 NP_001171805 NP_612446


NP_001156487 NP_001156488 NP_001156489 NP_001346300

Location (UCSC)

Chr X: 102.71 – 102.72 Mb

Chr X: 134.74 – 134.75 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

G-protein coupled receptor-associated sorting protein 2 is a protein that in humans is encoded by the GPRASP2 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000158301 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000072966 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Simonin F, Karcher P, Boeuf JJ, Matifas A, Kieffer BL (Apr 2004). "Identification of a novel family of G protein-coupled receptor associated sorting proteins". J Neurochem. 89 (3): 766–75. doi:10.1111/j.1471-4159.2004.02411.x. PMID 15086532.
^ "Entrez Gene: GPRASP2 G protein-coupled receptor associated sorting protein 2".

Further reading

Horn SC, Lalowski M, Goehler H, et al. (2007). "Huntingtin interacts with the receptor sorting family protein GASP2". Journal of Neural Transmission. 113 (8): 1081–90. doi:10.1007/s00702-006-0514-6. PMID 16835690. S2CID 9336547.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Goehler H, Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10.1016/j.molcel.2004.09.016. PMID 15383276.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.

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