INO80 complex subunit B

INO80B
Identifiers
AliasesINO80B, HMGA1L4, HMGIYL4, IES2, PAP-1BP, PAPA-1, ZNHIT4, hIes2, PAPA1, INO80 complex subunit B
External IDsOMIM: 616456; MGI: 1917270; GeneCards: INO80B
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_031288

NM_023547

RefSeq (protein)

NP_112578

NP_076036

Location (UCSC)Chr 2: 74.46 – 74.46 MbChr 6: 83.1 – 83.1 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

INO80 complex subunit B is a protein that in humans is encoded by the INO80B gene.[5]

INO80 stabilizes replication forks and counteracts mislocalization of H2A.Z

Function

This gene encodes a subunit of an ATP-dependent chromatin remodeling complex, INO80, which plays a role in DNA and nucleosome-activated ATPase activity and ATP-dependent nucleosome sliding. Readthrough transcription of this gene into the neighboring downstream gene, which encodes WW domain-binding protein 1, generates a non-coding transcript.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000115274Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030034Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: INO80 complex subunit B". Retrieved 2016-12-13.

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.