Isabella García-Manzo Gutiérrez was born in San Salvador, El Salvador.[2] Isabella García-Manzo is a daughter of Guatemalan businessman Andres García-Manzo and former beauty queen Natalia Gutiérrez who in 1994 represented the country of El Salvador in the Miss International beauty pageant.[4][5]
García-Manzo represented El Salvador at Miss Universe 2023, at the Adolfo Pineda National Gymnasium, El Salvador on 18 November 2023. She reached the top 10 semifinalists, becoming the first representative from the nation to place since Miss Universe 1996 and the fifth overall.[6]