The first documentary evidence of Jessen's existence dates to 1217. On the night of 20 to 21 September 1729, much of the town was destroyed in a fire. After belonging to Saxony for centuries, Jessen became Prussian in 1815.
In 1945, it became part of the Province (since 1947, State) of Saxony-Anhalt. In 1952, owing to East German administrative reforms, Jessen became a district capital in Bezirk Cottbus. In 1990, Jessen once again became part of the newly-refounded state of Saxony-Anhalt. In 1992 came the amalgamation of the communities of Grabo, Gorsdorf-Hemsendorf, Lindwerder and Großkorga, and in 1993, Schweinitz, Gerbisbach, Klossa, Schöneicho, Steinsdorf and Dixförda. With the district reform in 1994, Jessen became part of Wittenberg district, as well as having a further three communities melded with it, namely Battin, Düßnitz and Kleindröben-Mauken. In 1999 came further amalgamations: Arnsdorf, Leipa and Ruhlsdorf mit Rehain. On 1 March 2004 came a further 12, among them Seyda, Holzdorf and Linda (Elster). Some of these formerly independent communities themselves each consisted of more than one centre, and so Jessen now has a total of 47 Stadtteile (constituent communities).
Economy and infrastructure
Established businesses are mostly small and mid-sized concerns in metalworking, building, dairy processing and drink production. There are also, however, bigger enterprises in agriculture.