Sisco played high school football for the Riffel Royals before going to university.[1] He played four years of university football for the Rams at the University of Regina. In 30 career Canada West games with the Rams, Sisco had 141 catches for 2051 yards and 11 touchdown receptions to go along with eight rushing majors.[2] His best season with the Rams was in 2009, when he led the conference in receptions with 53 and in receiving yards with 700.[3] In his first year with the Rams, Sisco was named the club's Rookie of the Year. In 2008 and 2009, he was named a Canada West All-Star, and the team's top receiver.[3]