Merriweather began her coaching career as a graduate assistant at her alma mater Cincinnati in 2001. After spending one season with the Bearcats, she spent a season at UIC as an assistant before joining Purdue as an assistant coach and recruiting coordinator. Merriweather was suspended indefinitely during the 2005–06 season after she admitted to typing, correcting, and revising a paper for a point guard on the basketball team during the season, as well as making 105 impermissible phone calls to recruits. As a result, Purdue was placed on probation for the next two seasons and Merriweather did not return to Purdue after the 2005–06 season.[3]
Wright State
After four seasons away from college basketball, Merriweather was hired as an assistant coach at Wright State in 2010.[4] She added recruiting coordinator duties in 2012.
Merriweather was promoted to head coach in 2016 after Mike Bradbury departed to accept the head coaching position at New Mexico.[5] At Wright State, she led the program to their first ever NCAA tournament win while also winning three Horizon League regular season titles and three Horizon League coach of the year awards.
Memphis
Merriweather was named the head coach at Memphis on March 29, 2021, the 12th head coach in program history.[6]
Cincinnati
On March 25, 2023, Merriweather returned to Cincinnati to become the 10th head coach in the program's history.[7]
National champion
Postseason invitational champion
Conference regular season champion
Conference regular season and conference tournament champion
Division regular season champion
Division regular season and conference tournament champion
Conference tournament champion