KY 63 starts at the Tennessee state line, where the road continues southward as Tennessee State Route 56 (SR 56). Just north of that point is Gamaliel, where it intersects Bugtussle Road (KY 382), and begins its concurrency with KY 100. The two routes have intersections with KY 1860, and KY 1366 during the concurrency from Gamaliel to Tompkinsville. The two routes split at their junction with KY 375 (a former alignment of KY 163) in Tompkinsville. KY 63 turns northwestward to the KY 678 junction at Mount Hermon.
Most of the KY 63 corridor between Tompkinsville and Glasgow is recognized as a Kentucky Scenic Byway, which signifies that KY 63 provides a scenic drive through most of its course in Monroe and Barren counties. Also, KY 63, along with the first 10 miles (16 km) of KY 90 and parts of KY 70 between Mammoth Cave National Park and Cave City are parts of the "Cordell Hull Scenic Highway".
History
Since 1986, KY 63 from Tompkinsville to Glasgow, along with KY 90 northwest of Glasgow, is the core route of the annual Roller Coaster Yard Sale.[2]