LANCL1
| LANCL1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | LANCL1, GPR69A, p40, LanC like 1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 604155; MGI: 1336997; GeneCards: LANCL1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
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LanC like 1 is a protein that in humans is encoded by the LANCL1 gene.[5]
Function
This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000115365 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026000 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: LanC like 1". Retrieved 2016-04-20.
Further reading
- Zhang W, Wang L, Liu Y, Xu J, Zhu G, Cang H, Li X, Bartlam M, Hensley K, Li G, Rao Z, Zhang XC (2009). "Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione". Genes Dev. 23 (12): 1387–92. doi:10.1101/gad.1789209. PMC 2701572. PMID 19528316.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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