LPCAT1

LPCAT1
Identifiers
AliasesLPCAT1, lysophosphatidylcholine acyltransferase 1, AYTL2, PFAAP3, lpcat, AGPAT10, AGPAT9, LPCAT-1, lysoPAFAT, acyltransferase like 2
External IDsOMIM: 610472; MGI: 2384812; GeneCards: LPCAT1
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez

79888

210992

Ensembl

ENSG00000275079
ENSG00000153395

ENSMUSG00000021608

UniProt

Q8NF37

Q3TFD2

RefSeq (mRNA)

NM_024830

NM_145376
NM_001368681
NM_001368682

RefSeq (protein)

NP_079106

NP_663351
NP_001355610
NP_001355611

Location (UCSC)Chr 5: 1.46 – 1.52 MbChr 13: 73.62 – 73.66 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse
acyltransferase like 2
Identifiers
SymbolAYTL2
Alt. symbolsLPCAT
NCBI gene79888
HGNC25718
OMIM610472
RefSeqNM_024830
UniProtQ8NF37
Other data
EC number2.3.1.23
LocusChr. 5 p15.33
Search for
StructuresSwiss-model
DomainsInterPro

Lysophosphatidylcholine acyltransferase 1, also known as acyltransferase like 2, is a protein in humans that is encoded by the LPCAT1 gene.[5]

Lysophosphatidylcholine (LPC) acyltransferase (LPCAT; EC 2.3.1.23) catalyzes the conversion of LPC to phosphatidylcholine (PC) in the remodeling pathway of PC biosynthesis.[6]

See also

References

  1. ^ a b c ENSG00000153395 GRCh38: Ensembl release 89: ENSG00000275079, ENSG00000153395 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021608 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Lysophosphatidylcholine acyltransferase 1". Archived from the original on December 16, 2018.
  6. ^ Nakanishi H, Shindou H, Hishikawa D, Harayama T, Ogasawara R, Suwabe A, Taguchi R, Shimizu T (2006). "Cloning and characterization of mouse lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1). Expression in alveolar type II cells and possible involvement in surfactant production". J. Biol. Chem. 281 (29): 20140–7. doi:10.1074/jbc.M600225200. PMID 16704971.


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