UC Sampdoria is an Italian professional football club based in Genoa, Liguria, who play their matches in Stadio Luigi Ferraris. The club was formed in 1946 after a fusion between Sampierdarenese and Andrea Doria, and the club's formal debut in an official league was also in 1946.
Sampdoria has played 66 seasons in the Serie A, 12 seasons in the Serie B, 0 seasons in the Serie C (or equivalent), 0 seasons in the Serie D (or equivalent) and 0 seasons in lower competitions.
This list details the club's achievements in major competitions, and the top scorers for each season. Top scorers in bold were also the top scorers in the Italian league that season. Records of local or regional competitions are not included due to them being considered of less importance.