The Lt. Benjamin Locke Store is a historic building in Arlington, Massachusetts. It currently functions as a four-family private residence. The 2+1⁄2-story wood-frame structure was built in 1816 by Lieutenant Benjamin Locke, son of Revolutionary War veteran Captain Benjamin Locke. He established it as a shop to take advantage of the recently established Middlesex Turnpike, which ran past its door. It was converted into a four-family residence in 1854, a role it continues to serve. In 1912, the house was designated as a "pest house" during a smallpox outbreak, but its use was not required.[2]