MFAP1

MFAP1

Identifiers

MFAP1, microfibrillar associated protein 1, microfibril associated protein 1, AMP

External IDs

OMIM: 600215; MGI: 1914782; GeneCards: MFAP1

Gene location (Human)

Chr.	Chromosome 15 (human)^[1]

Band	15q15.3	Start	43,804,492 bp^[1]
Band	15q15.3	End	43,824,690 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 2 (mouse)^[2]

Band	2\|2 E5	Start	121,322,392 bp^[2]
Band	2\|2 E5	End	121,337,146 bp^[2]

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

secondary oocyte

hair follicle

gonad

ventricular zone

cartilage tissue

epithelium of nasopharynx

amniotic fluid

germinal epithelium

Achilles tendon

right adrenal gland

Top expressed in

Rostral migratory stream

retinal pigment epithelium

ciliary body

vas deferens

human fetus

efferent ductule

iris

epithelium of lens

hand

lobe of prostate

More reference expression data


More reference expression data

Gene ontology
Molecular function	protein binding RNA binding
Cellular component	microfibril extracellular region nucleus spliceosomal complex U2-type precatalytic spliceosome
Biological process	biological process mRNA splicing, via spliceosome mRNA processing RNA splicing
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


4236


67532


ENSG00000140259


ENSMUSG00000068479


P55081


C0HKD8 C0HKD9

RefSeq (mRNA)


NM_005926


NM_026220

RefSeq (protein)


NP_005917


NP_001075444 NP_080496

Location (UCSC)

Chr 15: 43.8 – 43.82 Mb

Chr 2: 121.32 – 121.34 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Microfibrillar-associated protein 1 is a protein that in humans is encoded by the MFAP1 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000140259 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000068479 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Yeh H, Chow M, Abrams WR, Fan J, Foster J, Mitchell H, Muenke M, Rosenbloom J (Feb 1995). "Structure of the human gene encoding the associated microfibrillar protein (MFAP1) and localization to chromosome 15q15-q21". Genomics. 23 (2): 443–9. doi:10.1006/geno.1994.1521. PMID 7835894.
^ "Entrez Gene: MFAP1 microfibrillar-associated protein 1".

Further reading

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. Bibcode:2004CBio...14.1436J. CiteSeerX 10.1.1.323.5263. doi:10.1016/j.cub.2004.07.051. PMID 15324660. S2CID 2371325. {{cite journal}}: Cite uses deprecated parameter |citeseerx= (help)
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Weinmann AS, Yan PS, Oberley MJ, et al. (2002). "Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis". Genes Dev. 16 (2): 235–44. doi:10.1101/gad.943102. PMC 155318. PMID 11799066.

This article on a gene on human chromosome 15 is a stub. You can help Wikipedia by adding missing information.

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.