She began her career with the Agricultural Research Service Systematic Entomology Laboratory as a research scientist in 1986.[4] After completing her PhD in 1989, Solis was promoted to research entomologist with emphasis in snout moths,[4] and after serving as acting research leader of SEL in 2003, became a permanent research leader in 2005. She returned to full-time research in 2014.[1]
Maria Alma Solis was elected a fellow of the Entomological Society of America in 2018.[3][1] In 1991, she received a Certificate of Merit from the U.S. Department of Agriculture for outstanding performance.[4] While conducting fieldwork in Northern Mexico she assisted with development of an organismal program for the South Texas Engineering, Math, and Science program for high school students funded by National Aeronautical Space Administration in collaboration with the Gorgas Science Foundation.[4]