Maseko is a member of the Democratic Alliance. She worked as a project coordinator in the housing department of the Cederberg Local Municipality until her appointment as a proportional representation councillor in 2012.[2]
In 2014, she was elected to the Western Cape Provincial Parliament.[3] She was then elected chairperson of the legislature's Standing Committee on Human Settlements. Maseko remained in the position following her re-election in 2019.[2] During her second term in the provincial parliament, she also served as the DA's caucus chairperson.[4]