The village was established in 1970 by members of the Ezra youth movement and was the first village in the Mateh Binyamin council area. It moved to the present site in 1974.[7] It is named after the biblical Beit Horon (Joshua 10:10), the modern Arab villages of Bayt 'Ur al-Foqa and al-Tahta.
Some Palestinians managed to return to the area after their expulsion from the villages of Yalo, Imwas and Bayt Nuba on whose lands the moshav was established, and gained employment as farm hands at Mevo Horon in the 1980s. During the early stages of the Al Aqsa Intifada, when the main checkpoint into Israel was moved several kilometers east of Mevo Horon and further into the West Bank, the moshav made arrangements to pick up these workers at the new checkpoint, though since they lacked Israeli work permits, difficulties arose.[8]
On 7 June 2018 residents of Mevo Horon and Israeli descendants of Dutch Jews inaugurated the town's Chasdei Enosh synagogue, which is an exact replica of the synagogue that once stood in Terborg, in the Netherlands.[9] The original in Terborg was hit by an American bomb on 8 March 1945 and was not reconstructed because there were no longer ten adult Jewish men in Terborg in order to reestablish services. In 1958, after the demolition of the ruins, an office building was erected at the location. A stolperstein marks the former location of the synagogue in Terborg.[10]
^Carta's Official Guide to Israel and Complete Gazetteer to all Sites in the Holy Land. (3rd edition 1993) Jerusalem, Carta, p.325, ISBN965-220-186-3 (English)