Microvascular occlusion

Microvascular occlusion
Microvascular occlusion
Specialty	Dermatology

Microvascular occlusion refers to conditions that can present with retiform purpura.^[1] It has been suggested that phenylephrine may be a cause.^[2]

Signs and symptoms

Microvascular occlusions appears as bland necrosis without inflammation and retiform purpura.^[3]

Causes

Microvascular occlusions can be caused by heparin-induced thrombocytopenia, cryoglobulinemia, angioinvasive organisms, embolization, disseminated intravascular coagulation, livedoid vasculopathy, cell occlusion syndromes, and iatrogenic causes.^[3]

Outlook

The outcomes of microvascular occlusions are usually influenced by the degree, length, nature of the underlying cause, and prompt and effective treatment.^[3]

References

^ Jean L. Bolognia; Joseph L. Jorizzo; Ronald P. Rapini (27 August 2003). Dermatology. Elsevier Health Sciences. pp. 390–. ISBN 978-0-323-02578-2. Retrieved 20 May 2011.
^ Kalajian, AH.; Turpen, KB.; Donovan, KO.; Malone, JC.; Callen, JP. (Oct 2007). "Phenylephrine-induced microvascular occlusion syndrome in a patient with a heterozygous factor V Leiden mutation". Arch Dermatol. 143 (10): 1314–7. doi:10.1001/archderm.143.10.1314. PMID 17938347.
^ ^a ^b ^c Dehghani, Shakiba; Abtahi-Naeini, Bahareh (2021). "COVID-19: A new cause of cutaneous microvascular occlusion syndrome". Journal of Research in Medical Sciences. 26 (1). Medknow: 119. doi:10.4103/jrms.jrms_560_21. ISSN 1735-1995. PMC 8765522.

External links

[BologniaJorizzo2003-1] Jean L. Bolognia; Joseph L. Jorizzo; Ronald P. Rapini (27 August 2003). Dermatology. Elsevier Health Sciences. pp. 390–. ISBN 978-0-323-02578-2. Retrieved 20 May 2011.

[2] Kalajian, AH.; Turpen, KB.; Donovan, KO.; Malone, JC.; Callen, JP. (Oct 2007). "Phenylephrine-induced microvascular occlusion syndrome in a patient with a heterozygous factor V Leiden mutation". Arch Dermatol. 143 (10): 1314–7. doi:10.1001/archderm.143.10.1314. PMID 17938347.

[Dehghani_Abtahi-Naeini_2021_p._119-3] Dehghani, Shakiba; Abtahi-Naeini, Bahareh (2021). "COVID-19: A new cause of cutaneous microvascular occlusion syndrome". Journal of Research in Medical Sciences. 26 (1). Medknow: 119. doi:10.4103/jrms.jrms_560_21. ISSN 1735-1995. PMC 8765522.

[1]

[2]