Ingram grew up in Baltimore[2] in a blended family of six children; her mother worked at childcare and her stepfather worked in city operations. At age 10, her mother and a teacher at Windsor Hills Elementary enrolled her in an after-school theater program.[1] She later attended the Baltimore School for the Arts,[1][3] graduating in 2012.[4]
Due to financial limitations, Ingram declined an offer to attend Howard University and enrolled at Baltimore City Community College in 2012. Although Baltimore City did not have a drama program, she was encouraged by her advisor to continue acting and audition for local plays. She also took on multiple part-time jobs and scholarships to fund her schooling. She graduated with an associate degree.[1]
In 2015, she won a regional competition from the National Society of Arts and Letters, and finished fourth in the nationals. The winner of that competition, Jonathan Majors, encouraged her to audition for the Yale School of Drama. She was accepted with scholarship support and enrolled in the fall of 2016.[1]
Before starting Yale, she renamed herself Moses, after the biblical figure. "So when we got to school [Yale] they wanted us to register our names because this is the first time they would be publicized so people can see them. And before I got to Yale I had, had such a time just trying to make things work that my name just didn’t feel suited. So I prayed and asked God, 'What is it? I know it's not my name now, but it is something.' And a few days later, I just heard Moses in my head and that was it."[5]
Ingram appeared in the Disney+Star Wars spin-off miniseries Obi-Wan Kenobi as Reva Sevander / the Third Sister, an Inquisitor who works to hunt down surviving Jedi after Order 66. For her role as Reva Sevander in that series, Ingram received hundreds of direct messages on Instagram containing death threats and racist abuse which she revealed examples of on May 31, 2022. This prompted Disney and her colleagues, including Ewan McGregor, to defend her.[13][14] McGregor, in a video posted to the official Star Wars social media accounts, called the abusive messages "horrendous" and said that "if you’re sending her bullying messages, you’re no Star Wars fan in my mind".[15] For her performance in the miniseries, she received the Saturn Award for Best Supporting Actress in a Streaming Television Series.