In addition to Swenson, Frank Butler was heard in the role of Dave Arnold[6] (a sergeant who was Mr. Chameleon's assistant[7]), and Richard Keith portrayed the police commissioner. The announcers were George Bryan, Howard Claney, and Roger Knapp. The program was directed by Richard Leonard and written by Marie Baumer.[1]Victor Arden's orchestra provided music.[6]
A review of the premiere episode in the trade publication Variety said that the cast "turns in graphic characterizations" and rated the quality of production as "Grade A throughout".[8] The review said that the show had the ingredients to make it successful.[8]
A review in the trade publication Billboard during the fourth year of Mr. Chameleon described it as "actually nothing but a night time soap opera in the camouflage of a weekly mystery series."[9] It said that in the specific episode being reviewed, "Script, performance and production were all ridiculously melodramatic and devoid of any real character or animation."[9] The reviewer also wrote that the title character used too many cliches, had too much self confidence, and was a "stuffy individual".[9]