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NOC2L
Identifiers
Aliases	NOC2L, NET15, NET7, NIR, PPP1R112, NOC2 like nucleolar associated transcriptional repressor
External IDs	OMIM: 610770; MGI: 1931051; GeneCards: NOC2L
Gene location (Human)
Chr.	Chromosome 1 (human)
End	959,309 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	156,332,073 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; left testis; ; right testis; ; right hemisphere of cerebellum; ; skin of leg; ; gastrocnemius muscle; ; skin of abdomen; ; anterior pituitary; ; right lobe of liver; ; canal of the cervix;
	Top expressed in
	ectoderm; ; otic vesicle; ; otic placode; ; saccule; ; tail of embryo; ; epiblast; ; yolk sac; ; ventricular zone; ; genital tubercle; ; superior frontal gyrus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	histone binding; nucleosome binding; chromatin binding; protein binding; transcription corepressor activity; RNA binding;
Cellular component	Noc1p-Noc2p complex; Noc2p-Noc3p complex; nucleolus; nucleus; nucleoplasm; cytosol;
Biological process	cellular response to UV; negative regulation of B cell apoptotic process; negative regulation of histone acetylation; negative regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; transcription, DNA-templated; negative regulation of intrinsic apoptotic signaling pathway; apoptotic process; ribosomal large subunit biogenesis; regulation of signal transduction by p53 class mediator;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	26155
	57741
	ENSG00000188976
	ENSMUSG00000095567
	Q9Y3T9
	Q9WV70
	NM_015658
	NM_021303; NM_001369270
	NP_056473
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Nucleolar complex protein 2 homolog is a protein that in humans is encoded by the NOC2L gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000188976 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000095567 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)".

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Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
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Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
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Hublitz P, Kunowska N, Mayer UP, et al. (2006). "NIR is a novel INHAT repressor that modulates the transcriptional activity of p53". Genes Dev. 19 (23): 2912–24. doi:10.1101/gad.351205. PMC 1315397. PMID 16322561.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
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This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000188976 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000095567 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)".

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NOC2L

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