Mary Fanshawe (Fay Wray) is a dedicated, professional supervising nurse in an urban hospital. She is very friendly with one resident, Dr. Preston (Walter Byron), although it is clear that she is not his sole object of attention. Fanshawe reprimands one young nurse, Doris Andros (Mary Carlisle) for her careless attitude, but she is unaware that Andros and Preston are seeing one another in secret. Fanshawe is far less friendly with young Dr. Jim Barclay (Ralph Bellamy) despite his attentions toward her. Barclay, though, is also distracted by tensions with his superior, Dr. Walter Selby (Walter Connolly), who rejects the younger man's suggestions of trying more modern medical and surgical techniques.
During a crucial operation that Selby had insisted on performing himself, he finds himself unable to continue and hands the procedure to Barclay, who succeeds with a radically new technique, calmly observed by Fanshawe, who is acting as head nurse. Selby is forced to concede that his own time as a lead surgeon and hospital head has passed. Later, when a patient nearly commits suicide because of a mistake made by Andros, Barclay discovers the nurse with Preston, who was supposed to be on rounds in the ward, together on the hospital's rooftop.
Barclay attempts to cover for his fellow doctor, but when Andros learns she is to be fired, she threatens to expose the deceit. In the end, both Andros and Preston are forced to leave, with Fanshawe and Barclay now ready to collaborate both professionally and personally.
