The orchidometer was introduced in 1966 by Swiss pediatric endocrinologistAndrea Prader of the University of Zurich.[1] It consists of a string of twelve numbered wooden or plastic beads of increasing size from about 1 to 25 millilitres. Doctors sometimes informally refer to them as "Prader's balls", "the medical worry beads", or the "endocrine rosary".[2]
The beads are compared with the testicles of the patient, and the volume is read off the bead which matches most closely in size. Prepubertal sizes are 1–3 ml, pubertal sizes are considered 4 ml and up and adult sizes are 15-25 ml.[2]
The orchidometer can be used to accurately determine size of testes. Discrepancy of testicular size with other parameters of maturation can be an important clue to various diseases. Small testes can indicate either primary or secondary hypogonadism. Testicular size can help distinguish between different types of precocious puberty. Since testicular growth is typically the first physical sign of true puberty, one of the most common uses is as confirmation that puberty is beginning in a boy with delayed puberty. Large testes (macroorchidism) can be a clue to one of the most common causes of inherited generalised learning disability, fragile X syndrome.
^Page 16 in: Richter-Unruh, Annette; Doerfer, Jürgen; Schwab, Karl Otfried (2018). "Körperliche Entwicklung im Jugendalter" [Physical development in adolescence]. Jugendmedizin [Adolescent medicine] (in German). pp. 3–18. doi:10.1007/978-3-662-52783-2_1. ISBN978-3-662-52782-5.
Lin, Chih-Chieh; Huang, William J. S.; Chen, Kuang-Kuo (12 November 2009). "Measurement of Testicular Volume in Smaller Testes: How Accurate Is the Conventional Orchidometer?". Journal of Andrology. 30 (6): 685–689. doi:10.2164/jandrol.108.006460. PMID19578133.
Behre, H. M.; Nashan, Dorothée; Nieschlag, E. (December 1989). "Objective measurement of testicular volume by ultrasonography: evaluation of the technique and comparison with orchidometer estimates". International Journal of Andrology. 12 (6): 395–403. doi:10.1111/j.1365-2605.1989.tb01328.x. PMID2696729.
Sakamoto, Hideo; Saito, Katsuyuki; Ogawa, Yoshio; Yoshida, Hideki (January 2007). "Testicular Volume Measurements Using Prader Orchidometer Versus Ultrasonography in Patients with Infertility". Urology. 69 (1): 158–162. doi:10.1016/j.urology.2006.09.013. PMID17270640.
Diamond, David A.; Paltiel, Harriet J.; DiCanzio, James; Zurakowski, David; Bauer, Stuart B.; Atala, Anthony; Ephraim, Patti L.; Grant, Rosemary; Retik, Alan B. (September 2000). "Comparative Assessment of Pediatric Testicular Volume: Orchidometer Versus Ultrasound". Journal of Urology. 164 (3 Part 2): 1111–1114. doi:10.1016/S0022-5347(05)67264-3.