PDCD7

PDCD7
Identifiers
AliasesPDCD7, ES18, HES18, programmed cell death 7, 59K
External IDsOMIM: 608138; MGI: 1859170; GeneCards: PDCD7
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez

10081

50996

Ensembl

ENSG00000090470

ENSMUSG00000041837

UniProt

Q8N8D1

Q9WTY1

RefSeq (mRNA)

NM_005707

NM_016688

RefSeq (protein)

NP_005698

n/a

Location (UCSC)Chr 15: 65.12 – 65.13 MbChr 9: 65.25 – 65.27 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Programmed cell death protein 7 is a protein that in humans is encoded by the PDCD7 gene.[5][6]

This gene encodes a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signalling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000090470 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041837 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Park EJ, Kim JH, Seong RH, Kim CG, Park SD, Hong SH (Apr 1999). "Characterization of a novel mouse cDNA, ES18, involved in apoptotic cell death of T-cells". Nucleic Acids Res. 27 (6): 1524–30. doi:10.1093/nar/27.6.1524. PMC 148348. PMID 10037816.
  6. ^ a b "Entrez Gene: PDCD7 programmed cell death 7".

Further reading


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