Search Results: PDE4

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PDE4 inhibitor
Jumat, 2026-02-20 13:19:17

inhibitor, commonly referred to as a PDE4 inhibitor, is a drug used to block the degradative action of phosphodiesterase 4 (PDE4) on cyclic adenosine monophosphate...

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Phosphodiesterase 4
Sabtu, 2022-07-02 18:15:40

enzyme phosphodiesterase 4 (PDE4) are known: PDE4A PDE4B PDE4C PDE4D 3',5'-cyclic-AMP phosphodiesterase Phosphodiesterase (PDE) PDE4 inhibitor This set index...

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Phosphodiesterase inhibitor
Jumat, 2026-07-03 04:31:17

It inhibits PDE4 to the greatest extent, but also shows significant inhibition of other PDE subtypes, and so acts as a selective PDE4 inhibitor or a...

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Nerandomilast
Rabu, 2026-07-22 10:26:31

fibrosis and progressive pulmonary fibrosis. It is a phosphodiesterase 4 (PDE4) inhibitor. It is taken by mouth. Common side effects include diarrhea, decreased...

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List of phosphodiesterase inhibitors
Selasa, 2026-02-17 02:27:28

The following is a list of phosphodiesterase inhibitors. Adibendan Aminophylline Aminophylline dihydrate Amipizone Apremilast Arofylline Atizoram Befuraline...

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Mesembryanthemum tortuosum
Selasa, 2026-05-19 16:41:27

indication. Kanna shows potent inhibition of the serotonin transporter and PDE4. It promotes monoamine release through vesicular monoamine transporter-2...

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Apremilast
Selasa, 2025-12-23 22:12:53

The drug acts as a selective inhibitor of the enzyme phosphodiesterase 4 (PDE4). It is taken by mouth. Apremilast is indicated in the United States for...

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Cereblon E3 ligase modulator
Kamis, 2025-11-06 21:55:22

six-fold increase in PDE4 inhibitory activity. Sulfone group had similar PDE4 inhibition as the methyl ester group. The best PDE4 inhibition was observed...

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Chronic obstructive pulmonary disease
Rabu, 2026-08-05 00:42:24

(PDE4 inhibitors) are anti-inflammatories that improve lung function and reduce exacerbations in moderate-to-severe illness. Roflumilast is a PDE4 inhibitor...

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Chemoreceptor trigger zone
Minggu, 2026-05-17 04:43:55

phosphodiesterase 4 (PDE4) inhibitors, such as Rolipram, cause emesis as one of their side effects. It has been found that these PDE4 isoforms are expressed...

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Piclamilast
Rabu, 2025-12-31 21:05:40

Piclamilast (RP 73401), is a selective PDE4 inhibitor. It is comparable to other PDE4 inhibitors for its anti-inflammatory effects. It has been investigated...

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Ensifentrine
Sabtu, 2026-01-03 02:03:35

It is given by inhalation. PDE3 inhibitors act as bronchodilators, while PDE4 inhibitors have an anti-inflammatory effect. Ensifentrine was approved for...

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Difamilast
Minggu, 2026-07-26 11:06:11

atopic dermatitis. Difamilast is a non-steroidal topical phosphodiesterase 4 (PDE4) inhibitor. Difamilast was discovered and developed by Otsuka Pharmaceutical...

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Zatolmilast
Jumat, 2026-01-02 00:32:23

Silverberg JI, Eyerich K, Sommer MO, et al. (December 2023). "Next Generation PDE4 Inhibitors that Selectively Target PDE4B/D Subtypes: A Narrative Review"...

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Roflumilast
Minggu, 2026-08-02 21:04:48

September 2017. Retrieved 18 November 2013. Boswell-Smith V, Spina D (2007). "PDE4 inhibitors as potential therapeutic agents in the treatment of COPD-focus...

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Glaucine
Selasa, 2026-08-11 18:10:05

It is a non-competitive selective inhibitor of PDE4 in human bronchial tissue and granulocytes. PDE4 is an isoenzyme that hydrolyzes cyclic AMP to regulate...

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Psoriasis
Rabu, 2026-07-22 01:33:00

NJ, Griffiths CE (July 2015). "Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: Results...

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Rolipram
Jumat, 2025-12-26 00:23:10

used in research as a well-characterized PDE4 inhibitor. It has been used in studies to understand whether PDE4 inhibition could be useful in autoimmune...

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Serotonin reuptake inhibitor
Minggu, 2026-06-07 22:05:57

antagonist) Mesembrenone (also a weak PDE4 inhibitor (found in Sceletium tortuosum (kanna)) Mesembrine (also a weak PDE4 inhibitor (found in Sceletium tortuosum...

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3',5'-cyclic-AMP phosphodiesterase
Senin, 2026-08-03 11:01:43

cAMP-specific phosphodiesterase, cAMP-specific PDE, PDE1, PDE2A, PDE2B, PDE4, PDE7, PDE8, PDEB1, PDEB2) is an enzyme with systematic name 3′,5′-cyclic-AMP...

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Atopic dermatitis
Kamis, 2026-07-16 06:28:07

Janus kinase inhibitor, has uncertain efficacy and safety. Difamilast, a PDE4 inhibitor, was approved for medical use in Japan in September 2021, and in...

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Glial scar
Minggu, 2025-11-23 22:18:31

monophosphate (cAMP), a major intracellular signaling molecule; conversely, blocking PDE4 will increase cAMP. Increased intracellular cAMP levels in neurons has been...

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Mesembrine
Kamis, 2026-04-02 03:21:27

been found to behave as a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4) (Ki = 7,800 nM). A concentrated mesembrine extract of Sceletium tortuosum...

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Phosphodiesterase 3
Senin, 2026-08-10 01:32:23

PDEs (PDE3 and PDE4) that exhibited high affinities for cAMP were isolated. PDE3 exhibited high affinity for both cGMP and cAMP, but PDE4 had high affinity...

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Phosphodiesterase
Selasa, 2026-08-11 02:00:32

variety of fields (e.g. sildenafil as a PDE5 inhibitor and Rolipram as a PDE4 inhibitor). The PDE nomenclature signifies the PDE family with an Arabic...

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Sarcoidosis
Rabu, 2026-06-24 05:24:47

phosphodiesterase 4 (PDE4) inhibitors like apremilast (a thalidomide derivative), roflumilast, and the less subtype-selective PDE4 inhibitor, pentoxifylline...

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Tadalafil
Selasa, 2026-07-28 07:53:04

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Sildenafil
Jumat, 2026-07-24 06:27:31

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Etazolate
Rabu, 2025-12-24 12:00:02

and A2 subtypes, and as a phosphodiesterase inhibitor selective for the PDE4 isoform. It is currently in clinical trials for the treatment of Alzheimer's...

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Balipodect
Kamis, 2026-06-04 09:15:51

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Caffeine
Minggu, 2026-08-09 10:35:15

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Mesembrenone
Minggu, 2026-07-05 10:52:11

serotonin reuptake inhibitor; Ki = 27 nM) and also a phosphodiesterase 4 (PDE4) inhibitor (Ki = 470 nM). Other alkaloids present in Kanna include: Mesembrine...

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Dipropylcyclopentylxanthine
Senin, 2026-03-23 13:37:21

phosphodiesterase inhibitor, and is almost as potent as rolipram at inhibiting PDE4. It has been used to study the function of the adenosine A1 receptor in animals...

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List of investigational cognition and memory disorder drugs
Minggu, 2026-06-07 17:01:12

phosphodiesterase IV inhibitors - Dart NeuroScience – phosphodiesterase PDE4 inhibitors [47] Research programme: serotonin 6 receptor antagonists - GlaxoSmithKline...

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Psoriatic arthritis
Rabu, 2026-08-12 00:17:15

phosphodiesterase-4 inhibitor approved for use by the FDA in 2014. By inhibiting PDE4, an enzyme that breaks down cyclic adenosine monophosphate, cAMP levels rise...

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Biotie Therapies
Senin, 2026-07-27 17:19:47

(DBH). Ronomilast is a PDE4 inhibitor for chronic inflammatory disorders. It is a small molecule phosphodiesterase-4 inhibitor (PDE4). The product is developed...

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PDE9
Sabtu, 2026-06-27 12:47:43

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Cilomilast
Senin, 2026-01-19 22:01:35

used in the development of newer drugs. Cilomilast is a second-generation PDE4 inhibitor with anti-inflammatory effects that target bronchoconstriction...

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PDE4B
Minggu, 2025-10-05 08:40:58

bipolar disorder. PDE4B is believed to be the PDE4 subtype involved in the antipsychotic effects of PDE4 inhibitors such as rolipram. PDE4B is involved...

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Commonly prescribed drugs
Selasa, 2025-09-30 17:57:31

contraindications due to local action Phosphodiesterase-4 (PDE4) inhibitor Roflumilast Selectively blocking PDE4 on airway smooth muscles → increase intracellular...

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AKAP6
Selasa, 2025-07-15 10:49:53

Langeberg L K; Scott J D (April 2001). "mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module". EMBO J. 20 (8). England: 1921–30...

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Topical cream formulation
Jumat, 2025-10-03 17:26:11

Psoriasis Atopic dermatitis Other inflammatory skin diseases Targeted Immunotherapies PDE4 inhibitors; Jak inhibitors Psoriasis Atopic dermatitis (off label)...

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GYKI-13380
Senin, 2026-08-03 12:24:52

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Fenspiride
Kamis, 2025-12-25 02:34:23

have activity as an alpha-1 blocker, H1 antagonist, it also inhibits PDE3, PDE4, PDE5 with -logIC50 values of 3.44, 4.16, 3.8 respectively. Montes B, Catalan...

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CGMP-specific phosphodiesterase type 5
Sabtu, 2026-06-06 03:50:14

phosphodiesterases (10-fold for PDE6, >80-fold for PDE1, >700-fold for PDE2, PDE3, PDE4, PDE7, PDE8, PDE9, PDE10, and PDE11). The approximately 4,000-fold selectivity...

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MK-8189
Kamis, 2026-06-04 09:03:50

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Tofisopam
Selasa, 2026-06-02 08:06:05

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Theobromine
Senin, 2026-03-23 13:59:39

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Mufemilast
Kamis, 2026-01-08 11:50:41

Donglei; Hu, Pei; Wang, Hongyun; Jiang, Ji (1 June 2018). "Determination of a PDE4 inhibitor Hemay005 in human plasma and urine by UPLC-MS/MS and its application...

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Papaverine
Selasa, 2026-08-11 09:36:26

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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PDE7A
Senin, 2026-02-09 13:38:43

the PDE7 family, the other being PDE7B. The PDE7 family, along with the PDE4 and PDE8 families, are cAMP-specific, showing little to no activity against...

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Gemlapodect
Kamis, 2026-06-04 15:48:47

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Housing in South Africa
Rabu, 2026-07-29 05:22:53

Fidelity Fund Certificate (FFC) Meeting educational requirements (NQF4 and PDE4) Maintain a trust account with annual audits Adhere to a real estate practitioner...

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Crisaborole
Senin, 2026-05-11 23:24:00

8b00375. ISSN 1528-7483. Nazarian R, Weinberg JM (November 2009). "AN-2728, a PDE4 inhibitor for the potential topical treatment of psoriasis and atopic dermatitis"...

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Pentoxifylline
Minggu, 2026-06-28 05:40:22

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Theophylline
Rabu, 2026-08-05 16:16:42

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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List of investigational antipsychotics
Rabu, 2026-08-05 09:39:07

undefined mechanism of action – schizophrenia [83] CVL-047 – phosphodiesterase PDE4 inhibitor – schizophrenia [84] CY-150112 – undefined mechanism of action...

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RAP1GDS1
Kamis, 2025-07-17 01:27:27

functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis". Blood. 103 (7): 2661–7. doi:10.1182/blood-2003-06-2154...

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Disease-modifying antirheumatic drug
Rabu, 2026-01-21 20:08:17

anakinra IL-1 receptor antagonist bDMARD apremilast phosphodiesterase 4 (PDE4) inhibitor tsDMARD azathioprine Purine synthesis inhibitor unknown baricitinib...

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PDE5 inhibitor
Jumat, 2026-08-07 16:38:16

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Ibudilast
Sabtu, 2026-06-20 13:37:23

activation. Ibudilast acts as a phosphodiesterase inhibitor, inhibiting the PDE4 subtype to the greatest extent, but also showing significant inhibition of...

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PDE4D
Kamis, 2026-05-28 23:31:48

acrodysostosis. This is the subtype of PDE4 that appears to be involved in the emetic and antidepressant effects of PDE4 inhibitors. Furthermore, changes in...

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Moexipril
Sabtu, 2026-07-18 23:42:25

and kidney) activity has been shown after moexipril use. It has additional PDE4-inhibiting effects. The synthesis of the all-important dipeptide-like side...

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Atherosperminine
Sabtu, 2026-04-11 16:50:38

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Cilostazol
Sabtu, 2026-06-20 23:21:39

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Imperatorin
Minggu, 2025-09-28 04:55:21

throughput screening experiment for inhibitors of the phosphodiesterase PDE4. It displays a significant preference for PDE4B over PDE4A. Imperatorin has...

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PDE4A
Selasa, 2025-10-21 23:17:57

gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the secondary messenger, cAMP, which is a...

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Milrinone
Kamis, 2025-12-25 23:14:21

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Vardenafil
Jumat, 2026-07-24 10:03:39

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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KH-001
Minggu, 2026-03-15 13:51:08

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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EHNA
Rabu, 2026-07-01 03:21:49

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Icariin
Jumat, 2025-12-26 20:59:59

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Conditioned avoidance response test
Selasa, 2025-12-23 05:50:59

like pomaglumetad (LY-404039); and phosphodiesterase inhibitors like the PDE4 inhibitor rolipram and the PDE10A inhibitors papaverine, mardepodect (PF-2545920)...

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Osoresnontrine
Minggu, 2026-06-07 09:04:58

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Glaucium flavum
Sabtu, 2026-01-10 05:17:00

flavum. Glaucine has bronchodilator and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive...

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Pimobendan
Sabtu, 2026-05-02 05:36:14

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Drotaverine
Senin, 2026-07-27 23:19:33

Drotaverine (INN, also known as drotaverin) is an antispasmodic drug, used to enhance cervical dilation during childbirth and to relieve smooth muscle...

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List of investigational Parkinson's disease drugs
Minggu, 2026-08-09 16:23:19

inhibitor (NRI) [249] AVE-8112 (AVE8112; AVE-8112A) – phosphodiesterase PDE4 inhibitor [250] AX-201 (AX201) – nerve growth factor (NGF) stimulant [251]...

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List of investigational substance-related disorder drugs
Selasa, 2026-08-11 18:33:18

(AV-411; Eyevinal; Ibinal; KC-404; Ketas; MN-166; Pinatos) – phosphodiesterase PDE4 inhibitor, toll-like receptor 4 (TLR4) antagonist – alcoholism, opioid-related...

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Denise Manahan-Vaughan
Rabu, 2026-01-07 09:51:47

PMC 3377964. PMID 21917740. Wiescholleck V, Manahan-Vaughan D (November 2013). "PDE4 inhibition enhances hippocampal synaptic plasticity in vivo and rescues MK801-induced...

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List of investigational long COVID drugs
Rabu, 2026-07-29 10:28:17

(AV-411; Eyevinal; Ibinal; KC-404; Ketas; MN-166; Pinatos) – phosphodiesterase PDE4 inhibitor and toll-like receptor 4 (TLR4) antagonist [1] Sodium pyruvate...

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PDE1
Senin, 2026-03-30 04:21:05

1038/sj.ijir.3901208. PMID 15224129. Giembycz MA (June 2005). "Life after PDE4: overcoming adverse events with dual-specificity phosphodiesterase inhibitors"...

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Vinpocetine
Senin, 2026-08-03 01:29:45

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Clomipramine/sildenafil
Senin, 2026-02-02 14:10:10

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Aminophylline
Senin, 2025-12-29 03:44:49

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Dipyridamole
Jumat, 2026-01-02 08:34:04

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Avanafil
Selasa, 2026-08-11 22:30:04

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Diprophylline
Rabu, 2025-12-24 13:43:16

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Nitrosoprodenafil
Jumat, 2025-12-26 10:47:58

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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8-Cyclopentyl-1,3-dimethylxanthine
Minggu, 2025-12-21 14:16:27

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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PRKAR2A
Rabu, 2025-07-16 05:12:00

Langeberg LK, Scott JD (Apr 2001). "mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module". The EMBO Journal. 20 (8): 1921–30...

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Filaminast
Selasa, 2025-12-30 20:40:11

candidate developed by Wyeth-Ayerst. It is a phosphodiesterase 4 inhibitor (PDE4 inhibitor) and an analog of rolipram, which served as a prototype molecule...

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Zaprinast
Minggu, 2025-12-28 21:36:15

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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List of investigational headache and migraine drugs
Rabu, 2026-06-17 22:58:14

(AV-411; Eyevinal; Ibinal; KC-404; Ketas; MN-166; Pinatos) – phosphodiesterase PDE4 inhibitor – headache [51] IPX-232 – undefined mechanism of action – migraine...

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BRL-50481
Selasa, 2025-12-30 00:04:17

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Doxofylline
Jumat, 2026-01-30 02:07:58

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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ICI-63197
Selasa, 2025-05-27 12:40:15

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Udenafil
Senin, 2026-07-27 15:20:54

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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PDE11
Kamis, 2025-08-07 04:40:43

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Discovery and development of phosphodiesterase 5 inhibitors
Senin, 2026-05-04 01:55:16

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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BAY 73-6691
Minggu, 2026-06-21 14:58:27

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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List of investigational antidepressants
Jumat, 2026-08-07 03:34:20

receptor antagonist Rolipram (ME-3167; ZK-62711) – phosphodiesterase 4 (PDE4) inhibitor Sabcomeline (BCI-224; CEB-242; Memric; SB-202026) – muscarinic...

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Icos
Sabtu, 2026-08-08 01:46:10

occurring capsaicin analog, designed to treat interstitial cystitis. IC485, a PDE4 inhibitor, designed to treat emphysema, chronic bronchitis, chronic obstructive...

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Homosildenafil
Jumat, 2025-12-26 10:35:22

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Bucladesine
Jumat, 2026-01-02 20:01:56

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Trapidil
Jumat, 2025-12-26 21:52:01

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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PDE3 inhibitor
Kamis, 2025-09-25 16:35:04

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Zardaverine
Jumat, 2026-01-02 00:32:01

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Paraxanthine
Senin, 2026-07-27 03:38:01

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Phosphodiesterase 2
Senin, 2025-07-07 11:42:24

"Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral...

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Irsogladine
Rabu, 2025-12-31 01:50:47

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Cartazolate
Selasa, 2025-12-30 16:43:25

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Moxaverine
Sabtu, 2026-01-10 19:34:06

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Proxyphylline
Rabu, 2025-12-31 21:39:57

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Enoximone
Rabu, 2026-08-12 13:03:27

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Mirodenafil
Rabu, 2025-11-12 09:48:25

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Finasteride/tadalafil
Selasa, 2025-08-26 05:38:08

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Furafylline
Sabtu, 2026-01-03 02:25:19

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Kaang Bong-Kiun
Senin, 2026-08-03 13:38:20

was successful in finding the novel signaling molecules ApLLP, CAMAP, ApPDE4, and ApAUF1, which are involved in long-term facilitation. With his colleagues...

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T-0156
Kamis, 2025-10-02 21:15:47

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Pentifylline
Rabu, 2025-12-31 20:59:59

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Propentofylline
Selasa, 2026-07-21 20:14:48

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Anagrelide
Senin, 2025-12-29 03:46:26

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Acetildenafil
Kamis, 2025-12-25 00:23:52

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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8-Methoxymethyl-3-isobutyl-1-methylxanthine
Sabtu, 2026-07-04 03:16:21

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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SCH-51866
Selasa, 2025-08-26 02:47:07

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Apical dendrite
Selasa, 2026-03-17 03:12:33

were treated with Rolipram, a specific phosphodiesterase type IV inhibitor (PDE4 inhibitor), which resultes in the activation of protein kinase A (PKA) and...

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Trequinsin
Kamis, 2026-06-18 00:58:50

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Mardepodect
Kamis, 2026-06-04 09:27:13

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Enprofylline
Selasa, 2023-01-24 23:11:19

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Tracazolate
Jumat, 2026-03-06 13:25:18

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Quazinone
Sabtu, 2026-04-11 02:42:00

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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ADCY2
Selasa, 2025-07-22 19:25:29

ADCY2 to produce cAMP. The cAMP formed is degraded by phosphodiesterase 4 (PDE4) activated by an AKAP-anchored protein kinase A. Polymorphisms of the ADCY2...

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Lodenafil
Minggu, 2026-02-08 22:29:43

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Arofylline
Senin, 2025-09-01 17:00:19

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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IBMX
Selasa, 2025-07-15 20:34:13

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Siguazodan
Jumat, 2022-08-19 11:51:30

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Sulfoaildenafil
Jumat, 2025-12-26 10:44:27

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Outline of immunology
Rabu, 2025-10-22 17:44:19

Voclosporin Abetimus Gusperimus IMiDs Lenalidomide Pomalidomide Thalidomide PDE4 inhibitor Apremilast JAK inhibitors Baricitinib Deucravacitinib Deuruxolitinib...

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YM-976
Minggu, 2022-02-20 17:18:24

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Vesnarinone
Jumat, 2025-12-26 09:43:36

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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KMUP-1
Jumat, 2025-12-26 10:29:59

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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HT-0712
Selasa, 2025-12-30 21:20:16

anti-inflammatory program by Inflazyme Pharmaceuticals. HT-0712 appears to act as a PDE4 inhibitor, thereby increasing cAMP levels. When cAMP levels are increased...

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PDE10
Kamis, 2026-04-23 20:51:47

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Choline theophyllinate
Jumat, 2026-01-02 21:00:36

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Aildenafil
Rabu, 2026-01-28 07:21:10

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Amrinone
Senin, 2025-12-29 03:45:57

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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MY-5445
Rabu, 2025-07-16 17:58:51

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Cilostamide
Jumat, 2026-07-10 08:56:17

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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Atizoram
Minggu, 2023-11-05 03:22:21

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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CC-1088
Selasa, 2025-06-24 13:18:57

Pumafentrine Quazinone RPL-554 Siguazodan Trequinsin Vesnarinone Zardaverine PDE4 Apremilast Arofylline Atizoram Benafentrine Catramilast CC-1088 CDP-840 CGH-2466...

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