PRXL2B
| PRXL2B | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | PRXL2B, C1orf93, family with sequence similarity 213 member B, peroxiredoxin like 2B, FAM213B | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | MGI: 1913719; GeneCards: PRXL2B | |||||||||||||||||||||||||||||||||||||||||||||||||||||
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PRXL2B is a gene found in humans that encodes the enzyme prostamide/prostaglandin F synthase (EC 1.11.1.20).[5][6] Like prostaglandin F synthase (encoded by the gene AKR1C3), PRXL2B produces the labor inducing[7] hormone prostaglandin F2alpha, but differs from AKR1C3 in the substrates it uses to produce it.[5][8] PRXL2B catalyzes the following reaction:[5]
while, AKR1C3 instead uses prostaglandin D2 and NADPH (EC 1.11.1.188).[8]
References
- ^ a b c ENSG00000157870 GRCh38: Ensembl release 89: ENSG00000275125, ENSG00000157870 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029059 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b c "ENZYME entry: EC 1.1.1.20". enzyme.expasy.org. SIB Swiss Institute of Bioinformatics. Retrieved 2026-07-27.
- ^ "Entrez Gene: Peroxiredoxin like 2B". Retrieved 2018-10-19.
- ^ Thomas J, Fairclough A, Kavanagh J, Kelly AJ (2014). "Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term". Cochrane Database of Systematic Reviews. 2014 (6) CD003101. doi:10.1002/14651858.CD003101.pub3. PMC 7138281. PMID 24941907.
- ^ a b "ENZYME entry: EC 1.1.1.188". enzyme.expasy.org. SIB Swiss Institute of Bioinformatics. Retrieved 2026-07-27.
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